Results 21 to 30 of about 11,144,846 (357)

Migration of germline progenitor cells is directed by sphingosine-1-phosphate signalling in a basal chordate. [PDF]

, 2015
The colonial ascidian Botryllus schlosseri continuously regenerates entire bodies in an asexual budding process. The germ line of the newly developing bodies is derived from migrating germ cell precursors, but the signals governing this homing process ...
Bui, Connor, De Tomaso, Anthony W, Kassmer, Susannah H, Langenbacher, Adam D, Rodriguez, Delany   +4 more
core   +1 more source

Cell cycle regulation for meiosis in mammalian germ cells

The Journal of Reproduction and Development, 2023
In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells.
Ryuki SHIMADA, Kei-ichiro ISHIGURO
doaj   +1 more source

Role of β-catenin in post-meiotic male germ cell differentiation. [PDF]

PLoS ONE, 2011
Though roles of β-catenin signaling during testis development have been well established, relatively little is known about its role in postnatal testicular physiology.
Yao-Fu Chang, Jennifer S Lee-Chang, Krystle Y Harris, Amiya P Sinha-Hikim, Manjeet K Rao   +4 more
doaj   +1 more source

Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]

, 2011
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo, Fera, Stefania, Grisanti, Laura, Lucia Scaldaferri, Maria, Sanchez, Massimo, Stefanini, Mario, Vicini, Elena   +6 more
core   +2 more sources

SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells

Stem Cell Reports, 2017
In the seminiferous tubules of mouse testes, a population of glial cell line-derived neurotrophic factor family receptor alpha 1 (GFRα1)-positive spermatogonia harbors the stem cell functionality and supports continual spermatogenesis, likely independent
Moe Tokue, Kanako Ikami, Seiya Mizuno, Chiyo Takagi, Asuka Miyagi, Ritsuko Takada, Chiyo Noda, Yu Kitadate, Kenshiro Hara, Hiroko Mizuguchi, Takuya Sato, Makoto Mark Taketo, Fumihiro Sugiyama, Takehiko Ogawa, Satoru Kobayashi, Naoto Ueno, Satoru Takahashi, Shinji Takada, Shosei Yoshida   +18 more
doaj   +1 more source

Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary. [PDF]

PLoS ONE, 2014
The piRNA pathway plays an important role in maintaining genome stability in the germ line by silencing transposable elements (TEs) from fly to mammals.
Xing Ma, Su Wang, Trieu Do, Xiaoqing Song, Mayu Inaba, Yoshiya Nishimoto, Lu-ping Liu, Yuan Gao, Ying Mao, Hui Li, William McDowell, Jungeun Park, Kate Malanowski, Allison Peak, Anoja Perera, Hua Li, Karin Gaudenz, Jeff Haug, Yukiko Yamashita, Haifan Lin, Jian-quan Ni, Ting Xie   +21 more
doaj   +1 more source

Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin [PDF]

, 2008
Despite significant progress in identifying the guidance pathways that control cell migration, how a cell starts to move within an intact organism, acquires motility, and loses contact with its neighbors is poorly understood.
Barbosa, Vitor, Fuse, Naoyuki, Kunwar, Prabhat S., Lehmann, Ruth, Renault, Andrew D., Sano, Hiroko   +5 more
core   +3 more sources

Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

Scientific Reports, 2016
Introgression of farmed salmon escapees into wild stocks is a major threat to the genetic integrity of wild populations. Using germ cell-free fish in aquaculture may mitigate this problem.
A. Wargelius, S. Leininger, K. Skaftnesmo, L. Kleppe, E. Andersson, G. Taranger, R. Schulz, R. B. Edvardsen   +7 more
semanticscholar   +1 more source

DNA methylation and regulatory elements during chicken germline stem cell differentiation [PDF]

, 2018
Funding for Open Access provided by the UMD Libraries' Open Access Publishing Fund.The production of germ cells in vitro would open important new avenues for stem biology and human medicine, but the mechanisms of germ cell differentiation are not well ...
Cai, Wentao, Edwards, John, He, Yanghua, Lei, Jinzhi, Li, Bichun, Nie, Qing, Song, Jiuzhou, Zhao, Keji, Zuo, Qisheng   +8 more
core   +2 more sources

A pilgrim's progress: Seeking meaning in primordial germ cell migration

Stem Cell Research, 2017
Comparative studies of primordial germ cell (PGC) development across organisms in many phyla reveal surprising diversity in the route of migration, timing and underlying molecular mechanisms, suggesting that the process of migration itself is conserved ...
Andrea V. Cantú, Diana J. Laird
doaj   +1 more source