Results 21 to 30 of about 459,468 (342)

Cell cycle regulation for meiosis in mammalian germ cells

open access: yesThe Journal of Reproduction and Development, 2023
In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells.
Ryuki SHIMADA, Kei-ichiro ISHIGURO
doaj   +1 more source

Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin [PDF]

open access: yes, 2008
Despite significant progress in identifying the guidance pathways that control cell migration, how a cell starts to move within an intact organism, acquires motility, and loses contact with its neighbors is poorly understood.
Barbosa, Vitor   +5 more
core   +3 more sources

DNA methylation and regulatory elements during chicken germline stem cell differentiation [PDF]

open access: yes, 2018
Funding for Open Access provided by the UMD Libraries' Open Access Publishing Fund.The production of germ cells in vitro would open important new avenues for stem biology and human medicine, but the mechanisms of germ cell differentiation are not well ...
Cai, Wentao   +8 more
core   +2 more sources

piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm [PDF]

open access: yes, 2017
Piwi-interacting RNAs (piRNAs) and PIWI proteins play a crucial role in germ cells by repressing transposable elements and regulating gene expression. In Drosophila, maternal piRNAs are loaded into the embryo mostly bound to the PIWI protein Aubergine ...
Beilharz, Traude H.   +9 more
core   +3 more sources

Germ Cell Specification [PDF]

open access: yes, 2012
The germline of Caenorhabditis elegans derives from a single founder cell, the germline blastomere P(4). P(4) is the product of four asymmetric cleavages that divide the zygote into distinct somatic and germline (P) lineages. P(4) inherits a specialized cytoplasm ("germ plasm") containing maternally encoded proteins and RNAs.
Jennifer T. Wang, Geraldine Seydoux
openaire   +3 more sources

SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells

open access: yesStem Cell Reports, 2017
In the seminiferous tubules of mouse testes, a population of glial cell line-derived neurotrophic factor family receptor alpha 1 (GFRα1)-positive spermatogonia harbors the stem cell functionality and supports continual spermatogenesis, likely independent
Moe Tokue   +18 more
doaj   +1 more source

Role of β-catenin in post-meiotic male germ cell differentiation. [PDF]

open access: yesPLoS ONE, 2011
Though roles of β-catenin signaling during testis development have been well established, relatively little is known about its role in postnatal testicular physiology.
Yao-Fu Chang   +4 more
doaj   +1 more source

Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]

open access: yes, 2011
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo   +6 more
core   +2 more sources

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]

open access: yes, 2017
BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine   +5 more
core   +1 more source

Of Stem Cells and Germ Cells [PDF]

open access: yesReproduction in Domestic Animals, 2011
ContentsStem cells have an intrinsic capacity to self‐renew and can differentiate to at least one specialized cell type. Different types of stem cells exist that can be culturedin vitro. The identity of the stem cells is marked by their origin and differentiation potential.
openaire   +4 more sources

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