Results 11 to 20 of about 11,177 (230)

Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy [PDF]

Korean Journal of Pediatrics, 2015
PurposeTo evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study ...
Jinsup Kim, Na Hee Lee, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Jeong-Meen Seo, Suk-Koo Lee   +7 more
doaj   +1 more source

A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report

Journal of Cardiothoracic Surgery, 2023
Background Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations.
Parviz Mardani, Hooman Kamran, Rezvan Ghaderpanah, Bita Geramizadeh, Damoun Fouladi, Reza Shahriarirad, Armin Amirian   +6 more
doaj   +1 more source

Exploring the interdependencies of research funders in the UK [PDF]

, 2014
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P, Farrell, C, Garau, M, Grassano, N, Hernandez-Villafuerte, K, Hopkins, M M, Hutton, J, Lang, F, Mawer, A, Pateman, C, Rotolo, D, Shah, K, Sharp, T, Sussex, J   +13 more
core   +1 more source

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]

, 2018
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di, Clark, Amander T, Gell, Joanna J, Hunt, Timothy J, Zhao, Jasmine   +4 more
core   +2 more sources

Identification of ERβ1 and ERβ2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia

Reproductive Biology and Endocrinology, 2009
Background Estrogens exert a role on germ cell physiology of normal human testis through the mediation of the estrogen receptor (ER) beta subtypes. Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-
Rago Vittoria, Romeo Francesco, Giordano Francesca, Ferraro Aurora, Andò Sebastiano, Carpino Amalia   +5 more
doaj   +1 more source

A case series and literature review on 98 pediatric patients of germ cell tumor developing growing teratoma syndrome

Cancer Medicine, 2023
Introduction Malignant germ cell tumors (MGCTs) can develop either extracranially or intracranially. Growing teratoma syndrome (GTS) may develop in these patients following chemotherapy.
Ming‐Yun Hsieh, Hsin‐Hung Chen, Chih‐Ying Lee, Giun‐Yi Hung, Tsung‐Yen Chang, Shih‐Hsiang Chen, Jin‐Yao Lai, Tang‐Her Jaing, Chao‐Neng Cheng, Jiann‐Shiuh Chen, Hsin‐Lin Tsai, Ting‐Yen Yu, Ming‐Hsin Hou, Cheng‐Yin Ho, Hsiu‐Ju Yen   +14 more
doaj   +1 more source

Interpretation on embryonal tumors in the 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition)

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Embryonal tumors of central nervous system (CNS) are a class of highly heterogeneous brain tumors and the most common malignant brain tumors in children. Researches based on histology and molecular genetics can classify them. This kind of researches only
WANG Yang
doaj   +1 more source

ZBTB16 is a sensitive and specific marker in detection of metastatic and extragonadal yolk sac tumour [PDF]

, 2017
Aims Accurate histological diagnosis and classification of germ cell tumours (GCTs) is key to informing successful therapeutic and surveillance strategy. The modern therapeutic approach for yolk sac tumour (YST) is highly curative.
Aron, Manju, Idrees, Muhammad T., Priemer, David S., Wei, Christina, Xiao, Guang-Qian, Yang, Qi   +5 more
core   +1 more source

A prospective study on contrast-enhanced magnetic resonance imaging of testicular lesions: distinctive features of Leydig cell tumours [PDF]

, 2015
OBJECTIVES: Up to 20 % of incidentally found testicular lesions are benign Leydig cell tumours (LCTs). This study evaluates the role of contrast-enhanced magnetic resonance imaging (MRI) in the identification of LCTs in a large prospective cohort study.
BERNARDO, SILVIA, CANTISANI, VITO, CATALANO, Carlo, GIANFRILLI, DANIELE, ISIDORI, Andrea, LENZI, Andrea, MANGANARO, Lucia, POFI, RICCARDO, POZZA, CARLOTTA, SALDARI, MATTEO, Scialpi, M, VINCI , VALERIA   +11 more
core   +1 more source

Neonates with cancer and causes of death; lessons from 615 cases in the SEER databases [PDF]

, 2017
Neonatal tumors are rare with no standard treatment approaches to these diseases, and the patients experience poor outcomes. Our aim was to determine the distribution of cancers affecting neonates and compare survival between these cancers and older ...
Askin, Bresters, Buck, Drazen, Ferrari, Gigliotti, Isaacs, Isaacs, Isaacs, Isaacs, Johnson, Linden, Longo, Louis, Mili, Moore, Moore, Oi, Orbach, Parkes, Rankin, Roosen, Sande, Steliarova-Foucher, Thompson, Vormoor, Yu   +26 more
core   +1 more source