Results 41 to 50 of about 6,150,201 (261)
Cell Reports, 2017 Summary: Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we developed a mouse TGCT model featuring germ cell-specific Kras activation and Pten ...
Timothy M. Pierpont +15 more
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Germ Cell Tumor with Bronchial Fistula
Case Reports in Radiology, 2020 Germ cell tumors account for 15% of anterior mediastinum tumors. Fistulas are abnormal communications between two surfaces covered by the epithelium.
María Katherinne Flórez Leguía +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Drug therapy for intracranial germ cell tumor [PDF]
Intracranial germ cell tumor (IGCT) is an uncommon brain tumor, which is mostly found in male adolescents. The histology of IGCT can be divided into germinoma, mature teratoma, immature teratoma, teratoma with somatic-type malignancy, embryonic carcinoma,
core +1 more source
Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report
Journal of Medical Case Reports, 2017 Background Malignant ovarian germ cell tumor is a rare type of disease, which generally has a good prognosis due to the high chemosensitivity of this type of tumor.
Montassar Ghalleb +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Nonseminomatous germ cell tumor with seizure disorder and mental retardation
, 2009 We report a case of a patient who presented with anterior mediastinal mass, seizure disorder, and mental retardation. Computerized tomography-guided fine-needle aspiration biopsy of the mass showed nonseminomatous germ cell tumor.
Joshi J +3 more
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Analisis Ketahanan Hidup Tumor Testis Sel Germinal di RS Sardjito Periode 2007-2013
Indonesian Journal of Cancer, 2016 Objective: To know survival of germ cell testicle tumor at Sardjito hospital who had chemotherapy or radiotherapy and its factor which influenced their survival Method: From year 2007 until 2013, we collected patients with germ cell testicle tumor at ...
Denny Achmad Prayoga, HR Danarto
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source