Results 21 to 30 of about 6,150,201 (261)

Emerging Prognostic Biomarkers in Testicular Germ Cell Tumors: Looking Beyond Established Practice

Frontiers in Oncology, 2018
Testicular germ cell tumors are unique among solid cancers. Historically, this disease was deadly if progressed beyond the stage I. The implementation of cisplatin-based chemotherapy regimens has drastically changed the clinical outcome of metastatic ...
Michal Chovanec, Michal Chovanec, Costantine Albany, Michal Mego, Rodolfo Montironi, Alessia Cimadamore, Liang Cheng, Liang Cheng   +7 more
doaj   +1 more source

The translational repressor Cup is required for germ plasm assembly and germ cell development in Drosophila. [PDF]

, 2011
RNA localization is a cellular mechanism used to localize proteins to sub-cellular domains and to control protein synthesis regionally. In oocytes, RNA localization has profound implications for development, generating asymmetric protein distributions ...
Ottone, Cristina
core   +1 more source

A case report of recurrent testicular germ cell tumor in a patient with a history of primary pulmonary germ cell tumor and a review of the literature

Frontiers in Oncology
BackgroundCompared to testicular germ cell tumors, the incidence of extragonadal germ cell tumors (EGCTs) is relatively low. While the lungs are a common site for metastasis of malignant germ cell tumors, primary pulmonary germ cell tumors are extremely ...
Jian Tan, Jian Tan, Jinfeng Wu, Jinfeng Wu, Runqiang Yuan, Wei Li, Linfeng Li, Hongxing Huang, Hongxing Huang, Yangbai Lu   +9 more
doaj   +1 more source

Ovarian germ cell tumors with rhabdomyosarcomatous components and later development of growing teratoma syndrome: a case report

Journal of Medical Case Reports, 2012
Introduction Development of a sarcomatous component in a germ cell tumor is an uncommon phenomenon. Most cases reported have a grim prognosis. Growing teratoma syndrome is also an uncommon phenomenon and occurs in approximately 2% to 7% of non ...
Al-Jumaily Usama, Al-Hussaini Maysa, Ajlouni Fatenah, Abulruz Abdulrahman, Sultan Iyad   +4 more
doaj   +1 more source

Germ Cell Tumor [PDF]

, 2012
The book aims to provide an overview of current knowledge regarding germ cell tumors. It deals with the clinical presentations, treatment modalities, the biology and genetics of germ cell tumors in children and adults.

core   +1 more source

Testicular seminoma after the complete remission of extragonadal yolk sac tumor : a case report

BMC Urology, 2004
Background Between 2% and 5% of malignant germ-cell tumors in men arise at extragonadal sites. Of extragonadal germ cell tumors, testicular carcinoma in situ (CIS) are present in 31–42% of cases, and CIS are reported to have low sensitivity to ...
Yanaihara Hitoshi, Nakagawa Ken, Mitsuhashi Tomoko, Ueno Munehisa, Kuroda Isao, Tsukamoto Takuji, Deguchi Nobuhiro   +6 more
doaj   +1 more source

Familial testicular germ cell tumors in two brothers

IJU Case Reports, 2020
Introduction Two percent of testicular germ cell tumors occur in family clusters. Here, we report metachronous testicular germ cell tumors in two brothers.
Senji Hoshi, Vladimir Bilim, Kiyotsugu Hoshi, Isoji Sasagawa, Kotarou Otake, Daigo Chiba, Shinta Suenaga, Masahito Konno, Yuki Katsumata, Kento Morozumi, Jun Takemoto, Kenji Numahata, Keiichi Ito   +12 more
doaj   +1 more source

Epidemiology and treatment outcomes of testicular germ cell tumor at tertiary care center in Patna, India: A retrospective analysis

Asian Pacific Journal of Cancer Care, 2020
Background: Malignant testicular neoplasm constitutes about 1% of all cancers in male, but malignant germ cell tumors are most common tumors in adolescents and young adult males.
Dharmendra Singh, Pritanjali Singh, Avik Mandal   +2 more
doaj   +1 more source

Abstract 3703: A genomic characterization of testicular germ cell tumor immune microenvironment

, 2017
Testicular germ cell tumors (TGCT) are a histologically diverse set of tumors and the most common cancer type in young men. As part of the TCGA effort, we analyzed tumors from 133 patients including 4 patients with asynchronous double primary TGCTs (137 ...
Benjamin Vincent, Charles M. Perou, Daniel P. Hollern, Katie Hoadley, TCGA Testicular Germ Cell Tumor Analysis Working Group   +4 more
core   +1 more source

Cytogenetics of a malignant ovarian germ-cell tumor

, 1998
Cytogenetic investigation of a malignant ovarian tumor diagnosed as a mixed germ-cell tumor, composed of extensive choriocarcinoma and foci of yolk-sac tumor, revealed a highly abnormal chromosomal pattern.
van der Linden, HC, van der Veen, AY, van Doorn, LC, de Jong, B, van Echten, J, Hans C. van der Linden, Lena C. van Doorn, Jannie van Echten, Bauke de Jong, Anneke Y. van der Veen, Curt W. Burger   +10 more
core   +2 more sources