Results 21 to 30 of about 1,853,912 (306)
Nature Genetics, 2017 The international Testicular Cancer Consortium (TECAC) combined five published genome-wide association studies of testicular germ cell tumor (TGCT; 3,558 cases and 13,970 controls) to identify new susceptibility loci.
Zhaoming Wang +37 more
semanticscholar +1 more source
Future of testicular germ cell tumor incidence in the United States: Forecast through 2026
Cancer, 2017 Testicular germ cell tumors (TGCTs) are rare tumors in the general population but are the most commonly occurring malignancy among males between ages 15 and 44 years in the United States (US).
Armen A. Ghazarian +4 more
semanticscholar +1 more source
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics, 2017 Differences of Sex Development (DSD) includes a wide spectrum of etiologies and phenotypes. A subset of individuals with DSDs are predisposed to gonadal germ cell tumor (GCT).
L. Pyle, K. Nathanson
semanticscholar +1 more source
Germ cell determination and the developmental origin of germ cell tumors [PDF]
Development, 2021 ABSTRACT In each generation, the germline is tasked with producing somatic lineages that form the body, and segregating a population of cells for gametogenesis. During animal development, when do cells of the germline irreversibly commit to producing gametes?
Peter K. Nicholls, David C. Page
openaire +4 more sources
Case Reports in Urology, 2015 Bone metastasis is a rare entity in germ cell tumor of testis and is a poor prognostic site. It is usually associated with synchronous metastasis at other sites.
Dipti Rani Samanta +6 more
doaj +1 more source
Journal of Medical Case Reports, 2012 Introduction Development of a sarcomatous component in a germ cell tumor is an uncommon phenomenon. Most cases reported have a grim prognosis. Growing teratoma syndrome is also an uncommon phenomenon and occurs in approximately 2% to 7% of non ...
Al-Jumaily Usama +4 more
doaj +1 more source
Pure ovarian dysgerminoma in a postmenopausal patient: A case report and review of the management
Gynecologic Oncology Reports, 2022 Background: A pure ovarian dysgerminoma in a postmenopausal female is a rare phenomenon. Case: A 65-year-old female presented with a large pelvic mass. Following surgical debulking, the patient was diagnosed with FIGO Stage IIB ovarian dysgerminoma.
Jennifer Vaz +8 more
doaj +1 more source
Emerging Prognostic Biomarkers in Testicular Germ Cell Tumors: Looking Beyond Established Practice
Frontiers in Oncology, 2018 Testicular germ cell tumors are unique among solid cancers. Historically, this disease was deadly if progressed beyond the stage I. The implementation of cisplatin-based chemotherapy regimens has drastically changed the clinical outcome of metastatic ...
Michal Chovanec +7 more
doaj +1 more source
Use of high-dosage chemotherapy with autologous hematopoietic stem cell transplantation as a first-line therapy for the patients with poor-prognosis testicular tumors [PDF]
Vojnosanitetski Pregled, 2005 Background. High-dose chemotherapy followed by hematopoietic stem cell support can be used as a first-line treatment in patients with germ-cell tumor (GCT) with poor prognosis. Long-term survival rate is attained in 50% of these patients. The aim of this
Marjanović Slobodan +2 more
doaj +1 more source
Cancer Science, 2016 Tripartite motif 44 (TRIM44) is one of the TRIM family proteins that are involved in ubiquitination and degradation of target proteins by modulating E3 ubiquitin ligases. TRIM44 overexpression has been observed in various cancers.
Y. Yamada +11 more
semanticscholar +1 more source