Results 11 to 20 of about 1,853,912 (306)

Intracranial Teratoma in Young Adult Female: Case Report

Brazilian Neurosurgery, 2023
Intracranial teratoma corresponds to a type of germ cell tumor (GCT) of the central nervous system which is characterized by the presence of tissues derived from the germinal layers, which may have hair and adipose tissue inside, for example.
Nathan Kulkys Marques, Karine Haag, Leonardo Trindade Buffara, Chelin Auswaldt Steclan, André Possamai Della, Diogo Pasquali Nones, Oscar Nelson Reimann Junior, Gabriel Hoher Peres, Arlindo Américo de Oliveira, Amaurí Batista de Oliveira Júnior, Leonard Rocha Fonseca de Brito, Michael Ricardo Lang, Filipe Laurindo Cabral   +12 more
doaj   +1 more source

Bone marrow metastasis in a patient with non‐seminomatous testicular germ cell tumor

IJU Case Reports, 2022
Introduction Metastasis to the bone marrow is rare in testicular germ cell tumor patients. We report a case of a patient with a non‐seminomatous testicular germ cell tumor who presented with bone marrow metastases after intensive chemotherapy.
Takashi Ueda, Ippei Takada, Teruki Shimizu, Saya Ito, Atsuko Fujihara, Takumi Shiraishi, Terukazu Nakamura, Osamu Ukimura   +7 more
doaj   +1 more source

Origin of Subsequent Malignant Neoplasms in Patients with History of Testicular Germ Cell Tumor

Cancers, 2020
Simple Summary Although testicular germ cell tumor (TGCT) carries a high cure rate, some patients still die from it. We investigated the genetic landscape and cellular origins of cancers that develop later in life after treatment for TGCT and found ...
E. Umbreit, B. Siddiqui, Michael J. Hwang, Aron Y Joon, Tapati Maity, M. Westerman, K. Merriman, Hussam Alhasson, Joma Uthup, Tao Guo, Joseph A. Moore, J. Ward, J. Karam, C. Wood, L. Pisters, Miao Zhang, S. Tu   +16 more
semanticscholar   +1 more source

Survival of Testicular Pure Embryonal Carcinoma vs. Mixed Germ Cell Tumor Patients across All Stages

Medicina, 2023
Background and Objectives: The impact of pure histological subtypes in testicular non-seminoma germ cell tumors on survival, specifically regarding pure embryonal carcinoma, is not well established.
Cristina Cano Garcia, Andrea Panunzio, Stefano Tappero, Mattia Luca Piccinelli, Francesco Barletta, Reha-Baris Incesu, Kyle W. Law, Lukas Scheipner, Zhe Tian, Fred Saad, Shahrokh F. Shariat, Derya Tilki, Alberto Briganti, Ottavio De Cobelli, Carlo Terrone, Alessandro Antonelli, Severine Banek, Luis A. Kluth, Felix K. H. Chun, Pierre I. Karakiewicz   +19 more
doaj   +1 more source

Extragonadal mixed germ cell tumor presenting as large mass in the pelvic cavity

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2021
Extragonadal germ cell tumors are relatively rare tumor, which usually occurs in the mediastinum or retroperitoneum. In this report, we present a case of primary mixed germ cell tumor (GCT) arising in the pelvic cavity.
Roopak Aggarwal, Pinki Pandey, Savita Agarwal, Vandana Shukla, Vineet Chaturvedi, Somender Pal Singh   +5 more
doaj   +1 more source

The 2021 World Health Organization Classification of Tumors of the Thymus and Mediastinum: What's new in thymic epithelial, germ cell and mesenchymal tumors?

Journal of Thoracic Oncology, 2021
This overview of the 5th edition of the WHO Classification of thymic epithelial tumors (TETs, including thymomas, thymic carcinomas (TCs) and thymic neuroendocrine tumors (NETs)), mediastinal germ cell tumors (GCTs) and mesenchymal neoplasms aims to 1 ...
A. Marx, J. C. Chan, L. Chalabreysse, S. Dacic, F. Detterbeck, C. French, J. Hornick, H. Inagaki, D. Jain, A. Lazar, M. Marino, E. Marom, A. Moreira, A. Nicholson, M. Noguchi, D. Nonaka, M. Papotti, S. Porubský, L. Sholl, H. Tateyama, V. Thomas de Montpréville, W. Travis, A. Rajan, A. Roden, P. Ströbel   +24 more
semanticscholar   +1 more source

Identification of 22 susceptibility loci associated with testicular germ cell tumors

Nature Communications, 2021
Testicular germ cell tumors (TGCT) are the most common tumor in young white men and have a high heritability. In this study, the international Testicular Cancer Consortium assemble 10,156 and 179,683 men with and without TGCT, respectively, for a genome ...
J. Pluta, L. Pyle, K. Nead, R. Wilf, Mingyao Li, N. Mitra, B. Weathers, K. D’Andrea, K. Almstrup, L. Anson-Cartwright, J. Benítez, Christopher D. Brown, S. Chanock, Chu Chen, V. Cortessis, A. Ferlin, C. Foresta, M. Gamulin, J. Gietema, Chiara Grasso, M. Greene, T. Grotmol, R. Hamilton, T. B. Haugen, R. Hauser, M. Hildebrandt, Matthew E Johnson, R. Karlsson, L. Kiemeney, D. Lessel, R. Lothe, J. Loud, C. Loveday, P. Martín-Gimeno, C. Meijer, J. Nsengimana, D. Quinn, T. Rafnar, S. Ramdas, L. Richiardi, R. Skotheim, K. Stefánsson, C. Turnbull, D. Vaughn, F. Wiklund, Xifeng Wu, Daphne Yang, T. Zheng, A. Wells, S. Grant, E. Rajpert-De Meyts, S. Schwartz, D. Bishop, K. McGlynn, P. Kanetsky, K. Nathanson, C. Kubisch   +56 more
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Pembrolizumab in Patients with Advanced Metastatic Germ Cell Tumors.

The Oncologist, 2021
LESSONS LEARNED Advanced germ cell tumors are aggressive and associated with poor prognosis. Pembrolizumab was overall well-tolerated in 12 heavily pretreated patients.
A. Tsimberidou, H. Vo, V. Subbiah, F. Janku, S. Piha-Paul, B. Yılmaz, Jing Gong, Mohammad Faraz Naqvi, S. Tu, M. Campbell, F. Meric-Bernstam, A. Naing   +11 more
semanticscholar   +1 more source

Identification and Validation Model for Informative Liquid Biopsy-Based microRNA Biomarkers: Insights from Germ Cell Tumor In Vitro, In Vivo and Patient-Derived Data

Cells, 2019
Liquid biopsy-based biomarkers, such as microRNAs, represent valuable tools for patient management, but often do not make it to integration in the clinic.
J. Lobo, A. Gillis, Annette van den Berg, L. Dorssers, G. Belge, K. Dieckmann, H. Roest, Luc J. W. van der Laan, J. Gietema, R. Hamilton, C. Jerónimo, R. Henrique, D. Salvatori, L. Looijenga   +13 more
semanticscholar   +1 more source

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor

Nature Genetics, 2017
Genome-wide association studies (GWAS) have transformed understanding of susceptibility to testicular germ cell tumors (TGCTs), but much of the heritability remains unexplained.
Kevin Litchfield, Max Levy, Giulia Orlando, C. Loveday, P. Law, G. Migliorini, A. Holroyd, P. Broderick, R. Karlsson, T. B. Haugen, W. Kristiansen, J. Nsengimana, K. Fenwick, I. Assiotis, Z. Kote-Jarai, A. Dunning, Kenneth R. Muir, J. Peto, R. Eeles, D. Easton, D. Dudakia, N. Orr, N. Pashayan, D. Bishop, A. Reid, R. Huddart, J. Shipley, T. Grotmol, F. Wiklund, R. Houlston, C. Turnbull   +30 more
semanticscholar   +1 more source