Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley +1 more source
Extracranial, Extragonadal Germ Cell Tumors: A Multicenter Australian Case Series. [PDF]
Chow KVC +19 more
europepmc +1 more source
ABSTRACT Background Immunotherapy response rates in head and neck squamous cell carcinoma (HNSCC) are limited by multiple factors. Tumor cell‐derived follistatin (FST) has been linked to immunotherapy resistance, but the underlying mechanisms remain poorly understood. This study aimed to investigate the prognostic value of FST and its associations with
Pan Song +6 more
wiley +1 more source
Toxicity of BEP chemotherapy in germ cell tumors: focus on immune-mediated bleomycin pulmonary toxicity in comparison with EP and VIP regimens. [PDF]
Olah P, Celec P, Vlkova B, Rejlekova K.
europepmc +1 more source
Large‐Scale Applications of Plasma Technologies: Progresses and Challenges
ABSTRACT Plasma technologies convert electrical power into energetic electrons, ions, reactive species, radiation and heat, thereby breaking through the bottleneck of purely thermal or chemical routes and bringing impressive changes to our world. This roadmap reviews the progress and challenges of plasma technologies from a large‐scale and application ...
Pankaj Attri +51 more
wiley +1 more source
Thromboembolic disease in testicular germ cell tumors-real-world evidence of three Portuguese institutions. [PDF]
Albuquerque J +11 more
europepmc +1 more source
Risk of Cancer With Hormone Replacement Therapy: A Narrative Review
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue +3 more
wiley +1 more source
Uncovering novel germline variants associated with testicular germ cell tumors by exome sequencing. [PDF]
Cuevas-Estrada B +13 more
europepmc +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source

