Results 1 to 10 of about 220,960 (266)

SGK1 is essential for meiotic resumption in mammalian oocytes

open access: yesEuropean Journal of Cell Biology, 2022
In mammalian females, oocytes are stored in the ovary and meiosis is arrested at the diplotene stage of prophase I. When females reach puberty oocytes are selectively recruited in cycles to grow, overcome the meiotic arrest, complete the first meiotic ...
Edgar del Llano   +8 more
doaj   +1 more source

Oocyte specific lncRNA variant Rose influences oocyte and embryo development

open access: yesNon-coding RNA Research, 2021
Fully grown mammalian oocytes store a large amount of RNA synthesized during the transcriptionally active growth stage. A large part of the stored RNA belongs to the long non-coding class which contain either transcriptional noise or important ...
Rajan Iyyappan   +5 more
doaj   +1 more source

Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review [PDF]

open access: yesCell Journal, 2022
Primordial germ cells develop into oocytes and sperm cells. These cells are useful resources in reproductive biology and regenerative medicine. The mesenchymal stem cells (MSCs) have been examined for in vitro production of primordial germ cell-like ...
Shabnam Fayezi   +3 more
doaj   +1 more source

Metabolic pathways regulating the development and non-genomic heritable traits of germ cells

open access: yesThe Journal of Reproduction and Development, 2021
Metabolism is an important cellular process necessary not only for producing energy and building blocks for cells, but also for regulating various cell functions, including intracellular signaling, epigenomic effects, and transcription.
Yasuhisa MATSUI, Yohei HAYASHI
doaj   +1 more source

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND: Mouse embryonic stem (ES) cells can differentiate into female and male germ cells in vitro. Primate ES cells can also differentiate into immature germ cells in vitro.
Kaori Yamauchi   +4 more
doaj   +1 more source

Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis. [PDF]

open access: yesPLoS ONE, 2009
In mammals, germ cells within the developing gonad follow a sexually dimorphic pathway. Germ cells in the murine ovary enter meiotic prophase during embryogenesis, whereas germ cells in the embryonic testis arrest in G0 of mitotic cell cycle and do not ...
Hui Li   +4 more
doaj   +1 more source

Wwc2 Is a Novel Cell Division Regulator During Preimplantation Mouse Embryo Lineage Formation and Oogenesis

open access: yesFrontiers in Cell and Developmental Biology, 2020
Formation of the hatching mouse blastocyst marks the end of preimplantation development, whereby previous cell cleavages culminate in the formation of three distinct cell lineages (trophectoderm, primitive endoderm and epiblast).
Giorgio Virnicchi   +5 more
doaj   +1 more source

Advances in Female Germ Cell Induction from Pluripotent Stem Cells

open access: yesStem Cells International, 2021
Germ cells are capable of maintaining species continuity through passing genetic and epigenetic information across generations. Female germ cells mainly develop during the embryonic stage and pass through subsequent developmental stages including ...
Maisumu Gulimiheranmu   +2 more
doaj   +1 more source

Dissecting chicken germ cell dynamics by combining a germ cell tracing transgenic chicken model with single-cell RNA sequencing

open access: yesComputational and Structural Biotechnology Journal, 2022
Avian germ cells can be distinguished by certain characteristics during development. On the basis of these characteristics, germ cells can be used for germline transmission.
Deivendran Rengaraj   +14 more
doaj   +1 more source

Germ Cell Specification [PDF]

open access: yes, 2012
The germline of Caenorhabditis elegans derives from a single founder cell, the germline blastomere P(4). P(4) is the product of four asymmetric cleavages that divide the zygote into distinct somatic and germline (P) lineages. P(4) inherits a specialized cytoplasm ("germ plasm") containing maternally encoded proteins and RNAs.
Jennifer T, Wang, Geraldine, Seydoux
openaire   +2 more sources

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