Results 271 to 280 of about 11,116,441 (355)

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Accepted Article.
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Oxidative Damage Under Microgravity Conditions: Response Mechanisms, Monitoring Methods and Countermeasures on Somatic and Germ Cells. [PDF]

Int J Mol Sci
Chen Z, Xie J, Ma C, Zhang P, Lei X.
europepmc   +1 more source

Supporting doctors' professional identity development through specialist training

Anatomical Sciences Education, EarlyView.
Abstract Anatomy‐centric specialties such as surgery, radiology, and anatomical pathology (AP) have workforce shortages, with attrition during the training phase proposed as a contributing factor. Current understanding of the reasons behind trainee attrition is limited, and there have been calls to increase the depth and richness of research in this ...
Shemona Y. Rozario, Melanie K. Farlie, Mahbub Sarkar, Michelle D. Lazarus   +3 more
wiley   +1 more source

Production of immune receptor knockout chickens via direct <i>in vivo</i> transfection of primordial germ cells. [PDF]

Anim Biotechnol
Jenkins K, Layton D, Gough T, O'Neil T, Malaver Otega L, Mishra K, Bruce K, Morris K, Wise T, Challagulla A, Doran T, Bean A.   +11 more
europepmc   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Hyperthermia suppresses the biological characteristics and migration of chicken primordial germ cells. [PDF]

Front Genome Ed
Gu Y, Wu K, Niu B, Wang Z, Jie Y, Fan Z, Li J, Sun C, Hou ZC, Shao LW.   +9 more
europepmc   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Primordial germ cells as a potential model for understanding (Nutri) epigenetic - metabolic interactions: a mini review. [PDF]

Front Cell Dev Biol
Ibrahim M, Grochowska E, Stadnicka K.
europepmc   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Chromatin environment-dependent effects of DOT1L on gene expression in male germ cells. [PDF]

Commun Biol
Coulée M, de la Iglesia A, Blanco M, Gobé C, Lapoujade C, Ialy-Radio C, Alvarez-Gonzalez L, Meurice G, Ruiz-Herrera A, Fouchet P, Cocquet J, El Khattabi L.   +11 more
europepmc   +1 more source