Results 21 to 30 of about 220,960 (266)

On the development of extragonadal and gonadal human germ cells

Biology Open, 2016
Human germ cells originate in an extragonadal location and have to migrate to colonize the gonadal primordia at around seven weeks of gestation (W7, or five weeks post conception).
A. Marijne Heeren, Nannan He, Aline F. de Souza, Angelique Goercharn-Ramlal, Liesbeth van Iperen, Matthias S. Roost, Maria M. Gomes Fernandes, Lucette A. J. van der Westerlaken, Susana M. Chuva de Sousa Lopes   +8 more
doaj   +1 more source

Primary Culture System for Germ Cells from Caenorhabditis elegans Tumorous Germline Mutants

Bio-Protocol, 2017
The Caenorhabditis elegans germ line is an important model system for the study of germ stem cells. Wild-type C. elegans germ cells are syncytial and therefore cannot be isolated in in vitro cultures. In contrast, the germ cells from tumorous mutants can
Alexandra Vagasi, Mohammad Rahman, Snehal Chaudhari, Edward Kipreos   +3 more
doaj   +1 more source

CPEB3 Maintains Developmental Competence of the Oocyte

Cells
Mammalian oocyte development depends on the temporally controlled translation of maternal transcripts, particularly in the coordination of meiotic and early embryonic development when transcription has ceased.
Lucie Lamacova, Denisa Jansova, Zongliang Jiang, Michal Dvoran, Daria Aleshkina, Rajan Iyyappan, Anna Jindrova, Heng-Yu Fan, Yuxuan Jiao, Andrej Susor   +9 more
doaj   +1 more source

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary. [PDF]

PLoS ONE, 2010
Female germ cells are essential for organogenesis of the ovary; without them, ovarian follicles do not form and functional and structural characteristics of the ovary are lost.
Chia-Feng Liu, Keith Parker, Humphrey H-C Yao   +2 more
doaj   +1 more source

Cell cycle regulation for meiosis in mammalian germ cells

The Journal of Reproduction and Development, 2023
In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells.
Ryuki SHIMADA, Kei-ichiro ISHIGURO
doaj   +1 more source

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary.

PLoS ONE, 2011
Differentiation of germ cells into male gonocytes or female oocytes is a central event in sexual reproduction. Proliferation and differentiation of fetal germ cells depend on the sex of the embryo.
Anne-Amandine Chassot, Elodie P Gregoire, Rowena Lavery, Makoto M Taketo, Dirk G de Rooij, Ian R Adams, Marie-Christine Chaboissier   +6 more
doaj   +1 more source

Optimization of In Vitro Culture Conditions of Sturgeon Germ Cells for Purpose of Surrogate Production

Animals, 2019
To expand germ cell populations and provide a consistent supply for transplantation, we established basal culture conditions for sturgeon germ cells and subsequently increased their mitotic activity by eliminating gonad somatic cells, supplementing with ...
Xuan Xie, Ping Li, Martin Pšenička, Huan Ye, Christoph Steinbach, Chuangju Li, Qiwei Wei   +6 more
doaj   +1 more source

Autophagy and apoptosis act as partners to induce germ cell death after heat stress in mice. [PDF]

PLoS ONE, 2012
Testicular heating suppresses spermatogenesis which is marked by germ cell loss via apoptotic pathways. Recently, it is reported that autophagy also can be induced by heat treatment in somatic cells.
Mianqiu Zhang, Min Jiang, Ye Bi, Hui Zhu, Zuomin Zhou, Jiahao Sha   +5 more
doaj   +1 more source

Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells. [PDF]

PLoS ONE, 2016
The mechanisms underlying human germ cell development are largely unknown, partly due to the scarcity of primordial germ cells and the inaccessibility of the human germline to genetic analysis.
Sarita Panula, Ahmed Reda, Jan-Bernd Stukenborg, Cyril Ramathal, Meena Sukhwani, Halima Albalushi, Daniel Edsgärd, Michiko Nakamura, Olle Söder, Kyle E Orwig, Shinya Yamanaka, Renee A Reijo Pera, Outi Hovatta   +12 more
doaj   +1 more source

Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8

eLife, 2023
Non-coding RNAs exert diverse functions in many cell types. In addition to transcription factors from coding genes, non-coding RNAs may also play essential roles in shaping and directing the fate of germ cells.
Nan Wang, Jing He, Xiaoyu Feng, Shengyou Liao, Yi Zhao, Fuchou Tang, Kehkooi Kee   +6 more
doaj   +1 more source