Results 21 to 30 of about 10,882,992 (336)
SGK1 is essential for meiotic resumption in mammalian oocytes
European Journal of Cell Biology, 2022 In mammalian females, oocytes are stored in the ovary and meiosis is arrested at the diplotene stage of prophase I. When females reach puberty oocytes are selectively recruited in cycles to grow, overcome the meiotic arrest, complete the first meiotic ...
Edgar del Llano +8 more
doaj
Germ cells in the teleost fish medaka have an inherent feminizing effect. [PDF]
PLoS Genetics, 2018 Germ cells are the only cells that can transfer genetic materials to the next generation via the sperm or egg. However, recent analyses in teleosts revealed another essential role of germ cells: feminizing the gonads.
Toshiya Nishimura +7 more
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Frontiers in Endocrinology, 2023 BackgroundSOX17 has been identified as a critical factor in specification of human primordial germ cells, but whether SOX17 regulates development of germ cells after sex differentiation is poorly understood. MethodsWe collected specimens of gonadal ridge
Ying-Yi Luo +9 more
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DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells
Cell Research, 2016 Chromatin remodeling is important for the epigenetic reprogramming of human primordial germ cells. However, the comprehensive chromatin state has not yet been analyzed for human fetal germ cells (FGCs).
Hongshan Guo +18 more
semanticscholar +1 more source
Stem cells of Hydra magnipapillata can differentiate into somatic cells and germ line cells [PDF]
, 1987 We investigated whether all stem cells of Hydra can differentiate both somatic cells and gametes or if a separate germ line exists in these phylogenetically old organisms.
Bode +28 more
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Oocyte specific lncRNA variant Rose influences oocyte and embryo development
Non-coding RNA Research, 2021 Fully grown mammalian oocytes store a large amount of RNA synthesized during the transcriptionally active growth stage. A large part of the stored RNA belongs to the long non-coding class which contain either transcriptional noise or important ...
Rajan Iyyappan +5 more
doaj
Primordial germ cells: the first cell lineage or the last cells standing?
Development, 2015 Embryos of many animal models express germ line determinants that suppress transcription and mediate early germ line commitment, which occurs before the somatic cell lineages are established.
Andrew D. Johnson, R. Alberio
semanticscholar +1 more source
The Journal of Poultry Science, 2001 Chicken primordial germ cells isolated from embryonic blood were cultured in vitro on feeder cells derived from the gonads of 7-day incubated embryos. Primordial germ cells were proliferated about 13 times during the 4 day culture period on the feeder ...
Mitsuru Naito +5 more
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Germ Cell Derivation from Pluripotent Stem Cells for Understanding In Vitro Gametogenesis
Cells, 2021 Assisted reproductive technologies (ARTs) have developed considerably in recent years; however, they cannot rectify germ cell aplasia, such as non-obstructive azoospermia (NOA) and oocyte maturation failure syndrome. In vitro gametogenesis is a promising
Tae-Kyung Hong +3 more
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piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells
Genes & Development, 2014 Transposable elements (TEs) occupy a large fraction of metazoan genomes and pose constant threats to genomic integrity. Small noncoding piwi-interacting RNAs (piRNAs) recognize and silence a diverse set of TEs in germ cells. Pezic et al.
Dubravka Pezic +3 more
semanticscholar +1 more source