Results 41 to 50 of about 10,882,992 (336)

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary. [PDF]

PLoS ONE, 2010
Female germ cells are essential for organogenesis of the ovary; without them, ovarian follicles do not form and functional and structural characteristics of the ovary are lost.
Chia-Feng Liu, Keith Parker, Humphrey H-C Yao   +2 more
doaj   +1 more source

Autophagy and apoptosis act as partners to induce germ cell death after heat stress in mice. [PDF]

PLoS ONE, 2012
Testicular heating suppresses spermatogenesis which is marked by germ cell loss via apoptotic pathways. Recently, it is reported that autophagy also can be induced by heat treatment in somatic cells.
Mianqiu Zhang, Min Jiang, Ye Bi, Hui Zhu, Zuomin Zhou, Jiahao Sha   +5 more
doaj   +1 more source

Oocyte formation by mitotically-active germ cells purified from ovaries of reproductive age women

Nature Network Boston, 2012
Germline stem cells that produce oocytes in vitro and fertilization-competent eggs in vivo have been identified in and isolated from adult mouse ovaries.
Yvonne A. R. White, D. Woods, Y. Takai, O. Ishihara, H. Seki, J. Tilly   +5 more
semanticscholar   +1 more source

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary.

PLoS ONE, 2011
Differentiation of germ cells into male gonocytes or female oocytes is a central event in sexual reproduction. Proliferation and differentiation of fetal germ cells depend on the sex of the embryo.
Anne-Amandine Chassot, Elodie P Gregoire, Rowena Lavery, Makoto M Taketo, Dirk G de Rooij, Ian R Adams, Marie-Christine Chaboissier   +6 more
doaj   +1 more source

Environmentally Induced Transgenerational Epigenetic Reprogramming of Primordial Germ Cells and the Subsequent Germ Line

PLoS ONE, 2013
A number of environmental factors (e.g. toxicants) have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation.
M. Skinner, Carlos Guerrero-Bosagna M. Haque, E. Nilsson, R. Bhandari, J. McCarrey   +4 more
semanticscholar   +1 more source

Sex Specification and Heterogeneity of Primordial Germ Cells in Mice.

PLoS ONE, 2015
In mice, primordial germ cells migrate into the genital ridges by embryonic day 13.5 (E13.5), where they are then subjected to a sex-specific fate with female and male primordial germ cells undergoing mitotic arrest and meiosis, respectively.
Akihiko Sakashita, Yukiko Kawabata, Yuko Jincho, Shiun Tajima, Soichiro Kumamoto, Hisato Kobayashi, Yasuhisa Matsui, Tomohiro Kono   +7 more
doaj   +1 more source

Optimization of In Vitro Culture Conditions of Sturgeon Germ Cells for Purpose of Surrogate Production

Animals, 2019
To expand germ cell populations and provide a consistent supply for transplantation, we established basal culture conditions for sturgeon germ cells and subsequently increased their mitotic activity by eliminating gonad somatic cells, supplementing with ...
Xuan Xie, Ping Li, Martin Pšenička, Huan Ye, Christoph Steinbach, Chuangju Li, Qiwei Wei   +6 more
doaj   +1 more source

Germinal Epithelium Cytology during Spermatogenesis in the Alligator Snapping Turtle, Macrochelys temminckii (Reptilia: Chelydridae) [PDF]

, 2018
We investigated the cytology of the seminiferous epithelia of the Alligator Snapping Turtle (Macrochelys temminckii). Spermatogenic and regressed testes were assessed from 2 adult individuals collected in Arkansas in May and September of 1993 ...
Gribbins, Kevin M., Trauth, Stanley E.
core   +3 more sources

Dissecting chicken germ cell dynamics by combining a germ cell tracing transgenic chicken model with single-cell RNA sequencing

Computational and Structural Biotechnology Journal, 2022
Avian germ cells can be distinguished by certain characteristics during development. On the basis of these characteristics, germ cells can be used for germline transmission.
Deivendran Rengaraj, Dong Gon Cha, Hong Jo Lee, Kyung Youn Lee, Yoon Ha Choi, Kyung Min Jung, Young Min Kim, Hee Jung Choi, Hyeon Jeong Choi, Eunhui Yoo, Seung Je Woo, Jin Se Park, Kyung Je Park, Jong Kyoung Kim, Jae Yong Han   +14 more
doaj  

Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells. [PDF]

PLoS ONE, 2016
The mechanisms underlying human germ cell development are largely unknown, partly due to the scarcity of primordial germ cells and the inaccessibility of the human germline to genetic analysis.
Sarita Panula, Ahmed Reda, Jan-Bernd Stukenborg, Cyril Ramathal, Meena Sukhwani, Halima Albalushi, Daniel Edsgärd, Michiko Nakamura, Olle Söder, Kyle E Orwig, Shinya Yamanaka, Renee A Reijo Pera, Outi Hovatta   +12 more
doaj   +1 more source