Results 41 to 50 of about 11,116,441 (355)
The Journal of Poultry Science, 2001 Chicken primordial germ cells isolated from embryonic blood were cultured in vitro on feeder cells derived from the gonads of 7-day incubated embryos. Primordial germ cells were proliferated about 13 times during the 4 day culture period on the feeder ...
Mitsuru Naito +5 more
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Germ cells in the teleost fish medaka have an inherent feminizing effect. [PDF]
PLoS Genetics, 2018 Germ cells are the only cells that can transfer genetic materials to the next generation via the sperm or egg. However, recent analyses in teleosts revealed another essential role of germ cells: feminizing the gonads.
Toshiya Nishimura +7 more
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Aquaculture Reports, 2021 The objective of this study was to understand germ cell renewal and differentiation in the Yesso scallop Mizuhopecten yessoensis throughout its reproductive cycle.
Mariia Mokrina +4 more
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Scientific Reports, 2015 The aim of this study was to assess the cellular miRNA expression behaviour in testes with spermatogenic failure (SpF). We performed a high-throughput screen of 623 mature miRNAs by a quantitative RT-qPCR-based approach in histologically well-defined ...
X. Muñoz +3 more
semanticscholar +1 more source
Germ Cell Derivation from Pluripotent Stem Cells for Understanding In Vitro Gametogenesis
Cells, 2021 Assisted reproductive technologies (ARTs) have developed considerably in recent years; however, they cannot rectify germ cell aplasia, such as non-obstructive azoospermia (NOA) and oocyte maturation failure syndrome. In vitro gametogenesis is a promising
Tae-Kyung Hong +3 more
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Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
Genes & Development, 1999 In many organisms the allocation of primordial germ cells (PGCs) is determined by the inheritance of maternal factors deposited in the egg. However, in mammals, inductive cell interactions are required around gastrulation to establish the germ line. Here,
K. Lawson +7 more
semanticscholar +1 more source
Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells.
PLoS Biology, 2003 In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad.
Prabhat S Kunwar +4 more
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Trade-off between somatic and germline repair in a vertebrate supports the "expensive germ line" hypothesis [PDF]
, 2020 The disposable soma theory is a central tenet of the biology of aging where germline immortality comes at the cost of an aging soma [T. B. L. Kirkwood, Nature 270, 301–304 (1977); T. B. L. Kirkwood, Proc. R. Soc. Lond. B Biol. Sci. 205, 531–546 (1979); T.
Bublys, Kasparas +4 more
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Primordial germ cells: the first cell lineage or the last cells standing?
Development, 2015 Embryos of many animal models express germ line determinants that suppress transcription and mediate early germ line commitment, which occurs before the somatic cell lineages are established.
Andrew D. Johnson, R. Alberio
semanticscholar +1 more source
WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary. [PDF]
PLoS ONE, 2010 Female germ cells are essential for organogenesis of the ovary; without them, ovarian follicles do not form and functional and structural characteristics of the ovary are lost.
Chia-Feng Liu +2 more
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