Results 201 to 210 of about 41,715 (245)

Multi-omics dissection of MAPK-driven senescence unveils therapeutic vulnerabilities in KIAA1549::BRAF-fusion pediatric low-grade glioma models. [PDF]

Signal Transduct Target Ther
Sigaud R, Stefanski A, Selt F, Kocher D, Usta D, Picard D, Büdenbender I, Remke M, Pfister SM, Jones DTW, Brummer T, Witt O, Milde T.   +12 more
europepmc   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
wiley   +1 more source

PD-L1 expression assessment in Angiosarcoma improves with artificial intelligence support. [PDF]

J Pathol Inform
Reith FH, Jarosch A, Albrecht JP, Ghoreschi F, Flörcken A, Dörr A, Roohani S, Schäfer FM, Öllinger R, Märdian S, Tielking K, Bischoff P, Frühauf N, Brandes F, Horst D, Sers C, Kainmüller D.   +16 more
europepmc   +1 more source

Single‐Cell RNA Sequencing Identifies MMP11+ Cancer‐Associated Fibroblasts as Drivers of Angiogenesis and Bladder Cancer Progression

Advanced Science, EarlyView.
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu, Ting Liang, Hu Fang, Lu Fu, Dashi Deng, Xiyang Tan, Lisha Liu, Dongdong Tang, Haoxiang Zheng, Qiuxia Ding, Xiuqi Hou, Daquan Feng, Tao Tao, Song Wu   +13 more
wiley   +1 more source

Digital Teaching and Learning Media for Nursing and Health Care Courses in Germany: Protocol for a Scoping Review.

JMIR Res Protoc
Vogel JN, Letzin J, Schmidt S.
europepmc   +1 more source

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

Tumour spectrum in <i>AKT1</i>-related Proteus syndrome: a systematic review of clinical reports and series. [PDF]

J Med Genet
Rostagni OM, Early CL, Hodges MB, Obasohan JO, Sapp JC, Livinski AA, Biesecker LG, Ours CA.   +7 more
europepmc   +1 more source

Treatment of Central Neurocytoma. [PDF]

Cancers (Basel)
Michel A, Rodemerk J, Rauschenbach L, Ketelauri P, Danylyak O, Jabbarli R, Dammann P, Uerschels AK, Darkwah Oppong M, Gembruch O, Ahmadipour Y, Junker A, Sure U, Wrede KH.   +13 more
europepmc   +1 more source

A national DREEM: exploring medical and dental students' perceptions on their learning environment across Hungary. [PDF]

BMC Med Educ
Dávidovics A, Makszin L, Németh T.
europepmc   +1 more source

The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals. [PDF]

Alzheimers Dement
Krüger DM, Pena-Centeno T, Liu S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher SL, Burkhardt S, Schütz AL, Wan Y, Shaw LM, Brodsky AS, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A, Alzheimer's Disease Neuroimaging Initiative.   +24 more
europepmc   +1 more source