Results 181 to 190 of about 1,022,480 (312)

PEtab-GUI: a graphical user interface to create, edit, and inspect PEtab parameter estimation problems. [PDF]

Bioinformatics
Jost PJ, Bergmann FT, Weindl D, Hasenauer J.   +3 more
europepmc   +1 more source

Student micro-publications in archival tradition-building. Project funding by the German Research Foundation

Authors: Dennis Hormuth and Gunnar B. Zimmermann At universities, students make up the largest group of people – at the University of Hamburg, for example, with over 42,000 enrolled students in the 2022/2023 academic year, compared to around 15,000 employees, including over 9,000 employees at the University Medical Center.
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Comparison of IA-2 Bridge ELISA and Radiobinding Assays for Progression Risk Assessment in Early-Stage Type 1 Diabetes. [PDF]

Diabetes Obes Metab
Bonifacio E, Scholz M, Weiss A, Ziegler AG.   +3 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

German Research Stay Supported by the Alexander von Humboldt Foundation

Journal of the Society of Materials Science, Japan, 2013
openaire   +2 more sources

German Research Foundation to fund three DNP-NMR devices for materials science [PDF]

MRS Bulletin, 2012
openaire   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Echocardiographic strain imaging and progression of atrial fibrillation in low-risk individuals. [PDF]

Int J Cardiol Heart Vasc
Ohlrogge AH, Seum F, van Vreeswijk NL, Csengeri D, Sinning C, Linz D, Rienstra M, Schnabel RB.   +7 more
europepmc   +1 more source