Results 191 to 200 of about 215,077 (307)

Prolonged Inflammation Associates With Greater Infarct Size and Poor Outcome After ST-Segment Elevation Myocardial Infarction. [PDF]

JACC Basic Transl Sci
Graesser C, Krefting J, Schwab M, Scheidhauer H, Novacek S, Armbruster NL, Hinterdobler J, Rapelius S, Romer A, Rumpf PM, Roski F, Lenz T, Voll F, Vilne B, Trenkwalder T, von Scheidt M, Xhepa E, Joner M, Cassese S, Steffens S, Weber C, Schunkert H, Ndrepepa G, Kastrati A, Kessler T, Moggio A, Sager HB.   +26 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

An in-depth analysis of the molecular changes induced by short-term calorie restriction before living kidney donation. [PDF]

NPJ Aging
Späth MR, Arjune S, Bohl K, Rinschen MM, Falk CS, Antczak P, Grundmann F, Kubacki T, Hoyer-Allo KJR, Ignarski M, Koehler FC, Kaufmann K, Bartram MP, Wagner T, Thomas M, Lackmann JW, Wahida A, Schmaderer C, Kemmner S, Kurschat CE, Benzing T, Stippel D, Burst V, Müller RU.   +23 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Prediction of cognitive outcome and progression to dementia using ω6-PUFA/ω3-PUFA ratio. [PDF]

Alzheimers Dement
Andrade V, Kleineidam L, Wagner-Thelen H, Ballarini T, Campos-Martin R, Martino-Adami P, Tripathi KP, Guyonnet S, Vellas B, Scherer M, Maier W, Pentzek M, Schmid M, Riedel-Heller S, Weyerer S, Bickel H, Wiese B, Egert S, Wagner M, Ramírez A.   +19 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Design and rationale of the WE-CARE-HF-CMR trial: Cardiorenal care on wheels for asymptomatic heart failure patients (NCT07185100). [PDF]

J Cardiovasc Magn Reson
Li JJ, Thiede G, Götze C, Exarchos V, Meuwly C, Werhahn SM, Beyer RE, Müller ML, Bigvava T, Stehning C, Remppis BA, Wieditz J, Sack S, Heer T, Sroka M, Nagel E, Hays AG, Duvigneau G, Blankenberg S, Steen H, Frey N, Baldus S, Seuthe K, Lorbach R, Rödicker F, Scharf S, Hilgendorf I, Landmesser U, Friede T, Falk V, Doeblin P, Kelle S.   +31 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Mapping neurogenic dysphagia diagnostics in Germany: accessibility, implementation practices, and barriers to swallowing endoscopy. [PDF]

Neurol Res Pract
Marae JG, Masanneck L, Pawlitzki M, Huber C, Hofacker J, Lapa S, Jung A, Muhle P, Suntrup-Krueger S, Warnecke T, Meuth SG, Dziewas R, Labeit B.   +12 more
europepmc   +1 more source

German Research Stay Supported by the Alexander von Humboldt Foundation

Journal of the Society of Materials Science, Japan, 2013
openaire   +2 more sources