Results 201 to 210 of about 215,077 (307)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Appendix300: Surgical video and patient metadata of 330 laparoscopic appendectomy cases from five institutions. [PDF]

Sci Data
Kolbinger FR, Kirchner M, Pfeiffer K, Bodenstedt S, Jenke AC, Barthel J, Carstens M, Dehlke K, Dietz S, Emmanouilidis S, Fitze G, Freitag M, Holderried F, Jacobi T, Kanjo W, Leitermann L, Mees ST, Pistorius S, Prudlo C, Seiberth A, Schultz J, Thiel K, Ziehn D, Speidel S, Weitz J, Kather JN, Distler M, Saldanha OL.   +27 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Response to Comment on Huttasch et al. Increased Early Postprandial Glucagon Concentrations in Humans With Newly Diagnosed Type 2 Diabetes and Steatotic Liver Disease. [PDF]

Diabetes Care
Huttasch M, Roden M.
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Analgosedation for catheter ablation in deep sedation: comparison between cryoballoon and pulsed field ablation. [PDF]

Europace
Nies M, Rottner L, Unruh I, Obergassel J, Rieß J, Schenker N, Ismaili D, Benesch Vidal ML, Christmann D, Skibowski J, Scharlemann L, Otto C, Kany S, Lemoine MD, Reißmann B, Ouyang F, Kirchhof P, Metzner A, Rillig A.   +18 more
europepmc   +1 more source

German Research Foundation to fund three DNP-NMR devices for materials science [PDF]

MRS Bulletin, 2012
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

How CAR T cells can be shielded from prostaglandin E2 signaling to enhance their therapeutic activity. [PDF]

Mol Ther Oncol
Dörr J, Andreu-Sanz D, Kobold S.
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source