Results 201 to 210 of about 1,018,571 (313)

Circulating cytokine levels and 5-year vascular recurrence after stroke: A multicenter prospective cohort study. [PDF]

Eur Stroke J
Zhang L, Antabi MA, Mattar J, El Bounkari O, Fang R, Waegemann K, Bode FJ, Stösser S, Hermann P, Liman TG, Nolte CH, Ikenberg B, Bernkopf K, Petzold GC, Bernhagen J, Dichgans M, Georgakis MK, DEMDAS Investigators .   +17 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Comparison Between Browser- and App-Based Versions of a Program for Self-Management of Mild to Moderate Depression: Log Data Analysis of a Convenience Sample.

JMIR Mhealth Uhealth
Scholze K, Allenhof C, Hegerl U.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

<i>German Million Children Cohort</i>: a historical birth cohort based on claims data to investigate the impact of immunisation and other early life factors on the risk of cancer and other diseases in childhood - cohort profile. [PDF]

BMJ Open
Brackmann LK, Mulanje L, Langbein S, Kollhorst B, Haug U, Ahrens W, Nagrani R, Marron M.   +7 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

ViMOP: a user-friendly and field-applicable pipeline for untargeted viral genome nanopore sequencing. [PDF]

Bioinformatics
Petersen NP, Le M, Renevey A, Emua E, Ryter S, Annibaldis G, Camara J, Boumbaly S, Erameh C, Laske T, Baumbach J, Lemey P, Günther S, Duraffour S, Kafetzopoulou LE.   +14 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

BRIDGE pilot study: a bilateral regulatory investigation of data governance and exchange. [PDF]

NPJ Digit Med
Hou HX, Bisson T, Leiss SM, Thierauf J, Stern AD, Strobelt H, Nensa F, Buyx A, Huster KM, Furlano K, Kozlakidis Z, Gupta S, Kostadinov D, Boor P, Slagman A, Tjardes T, Cholet P, Schneider NK, Schlomm T, Biskup S, Röhrig R, Molnár-Gábor F, Schmidt-Straßburger U, Ladewig K, Weigand M, Pinto Dos Santos D, Johnson JM, Kirsten T, Sutherland E, Zerbe N, Hofman A, Heyder R, Schmidt G, Lennerz JK.   +33 more
europepmc   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source