Results 171 to 180 of about 63,576 (258)

Extrafollicular and other non-germinal center B cell responses. [PDF]

J Immunol
Eisenbarth SC, Ashby KM, Ojo OA, Williams A.   +3 more
europepmc   +1 more source

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter, Hans Dorn, Julian Hellmann‐Regen, Ana Bueno‐Lopez, Verena van Ginneken, Heidi Danker‐Hopfe   +5 more
wiley   +1 more source

A spatial multi-omics atlas of immunosenescence reveals germinal-center B cell dysfunction in human lymph nodes. [PDF]

Cell Press Blue
Farzad N, Enninful A, Lu Y, Parisi F, Fung A, Kwon Y, Li Y, Labrosse M, Yang M, Strino F, Chen L, Yang J, Zhong M, Gao F, Tao B, Cunningham J, Bai Z, Li H, Wang F, Stankewich M, Kim D, Dong M, Bramer LM, Li K, Bhat MR, Loe E, Craft J, Pasa-Tolic L, Halene S, Shi L, Kluger Y, Xu ML, Fan R.   +32 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

B cell-intrinsic CXCR3 drives efficient generation of ectopic pulmonary germinal center responses to influenza A virus infection. [PDF]

Proc Natl Acad Sci U S A
Tyllis TS, Norton TS, Abbott C, McPeake DJ, Fenix KA, Wilson JJ, Kara EE, Good-Jacobson KL, Alsharifi M, McColl SR, Comerford I.   +10 more
europepmc   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

HnRNP A1 and A2B1 enforce Ezh2 mRNA splicing to promote germinal center B cell responses. [PDF]

Nat Commun
Zhu Z, Zhang R, Kang H, Chen M, Huang H, Wang J, Guo L, Li Y, Chen W, Meng L, Wang R, Li L, Lam KP, Xu S, Ou X.   +14 more
europepmc   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Differential role of CREBBP missense and truncating mutations in germinal center development and lymphomagenesis.

Blood
Yu C, Holloman M, Kim A, Chang Y, Meyer SN, Holmes AB, Cai B, Mo T, Basso K, Dreval K, Morin RD, Bhagat G, Mullighan CG, Dalla-Favera R, Pasqualucci L.   +14 more
europepmc   +1 more source

Non-canonical NF-κB drives a fate switch from germinal center to early effector B cells. [PDF]

iScience
Nawaz W, Fong A, Cardoso MP, Tang J, Zhao J, Li MY, Rai S, Beresford A, Alduaij W, Boyle M, Steidl C, Scott DW, Venturutti L.   +12 more
europepmc   +1 more source