Results 181 to 190 of about 4,714,009 (283)

Gap-Junction Communication Pathways in Germinal Center Reactions

Clinical and Developmental Immunology, 1998
Tibor Krenacs, Martin Rosendaal
doaj   +1 more source

B cell-intrinsic CXCR3 drives efficient generation of ectopic pulmonary germinal center responses to influenza A virus infection. [PDF]

Proc Natl Acad Sci U S A
Tyllis TS, Norton TS, Abbott C, McPeake DJ, Fenix KA, Wilson JJ, Kara EE, Good-Jacobson KL, Alsharifi M, McColl SR, Comerford I.   +10 more
europepmc   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

HnRNP A1 and A2B1 enforce Ezh2 mRNA splicing to promote germinal center B cell responses. [PDF]

Nat Commun
Zhu Z, Zhang R, Kang H, Chen M, Huang H, Wang J, Guo L, Li Y, Chen W, Meng L, Wang R, Li L, Lam KP, Xu S, Ou X.   +14 more
europepmc   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Non-canonical NF-κB drives a fate switch from germinal center to early effector B cells. [PDF]

iScience
Nawaz W, Fong A, Cardoso MP, Tang J, Zhao J, Li MY, Rai S, Beresford A, Alduaij W, Boyle M, Steidl C, Scott DW, Venturutti L.   +12 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Protocol for an in vivo CRISPR screen for germinal center B cells in mice using ecotropic retrovirus. [PDF]

STAR Protoc
Hong JP, Nussenzweig MC.
europepmc   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

AID and TET2 cooperate to demethylate Irf4 for plasma cell fate in germinal center B cells. [PDF]

J Exp Med
He M, D'Aulerio R, Pinho LG, Doukoumopoulos E, Yong T, Vieira RC, Oliveira MMS, Eiben L, Termote M, Galvani RG, Sedimbi S, Seitz C, Kuznetsov NV, Zuriaga MA, Kitamura D, Fuster JJ, Cotta-de-Almeida V, Ström L, Dosenovic P, Degn SE, Westerberg LS.   +20 more
europepmc   +1 more source