Results 201 to 210 of about 72,003 (345)

Phased fragility and stability of non-genetic B cell states in the germinal center accelerate the genetic evolution of antibodies. [PDF]

Cell Syst
Xiang MY, Vaidehi Narayanan H, Kesarwani V, Vanheusden R, Wang T, Hoffmann A.   +5 more
europepmc   +1 more source

Novel specialized cell state and spatial compartments within the germinal center

, 2020
Domenick E. Kennedy, Michael K. Okoreeh, Mark Maienschein‐Cline, Junting Ai, Margaret Veselits, Kaitlin C. McLean, Yogesh Dhungana, Hong Wang, Junmin Peng, Hongbo Chi, Malay Mandal, Marcus R. Clark   +11 more
openalex   +2 more sources

Germinal Center [PDF]

, 2020
openaire   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Epstein-Barr virus (EBV) infection causes human germinal center B cell-derived lymphomas in the absence of EBNA2 expression. [PDF]

Proc Natl Acad Sci U S A
Wang C, Bristol JA, Nelson SE, Chen T, Hendrickson C, Baiu DC, Riel M, Hayes M, Ranheim EA, Gumperz JE, Johannsen EC, Kenney SC.   +11 more
europepmc   +1 more source

Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria [PDF]

, 2019
Ann Ly, Yang Liao, Halina M. Pietrzak, Lisa J. Ioannidis, Tom Sidwell, Renee Gloury, Marcel Doerflinger, Tony Triglia, Raymond Z. Qin, Joanna R. Groom, Gabrielle T. Belz, Kim L. Good‐Jacobson, Wei Shi, Axel Kallies, Diana S. Hansen   +14 more
openalex   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Local antibody feedback enforces a checkpoint on affinity maturation in the germinal center and promotes epitope spreading. [PDF]

Immunity
Yan Y, Wang X, Xie Z, Bader DLV, Lim RH, Ma KM, Cottrell CA, Steichen JM, Xu L, Villavicencio PM, Akauliya M, Koo JH, Shen JM, Vernich A, Kalyuzhniy O, Allen JD, Albowaidey AA, Alicea A, Chen B, Georgeson E, Ellis-Pugh JR, Alavi N, Esposito A, Naili H, Phelps N, Kelley B, Kubitz M, Phan QA, Liguori A, Prum T, Tingle R, Lu D, Eskandarzadeh S, Liu X, Warner JE, Weldon SR, Himansu S, Crispin M, Nair U, Liu S, Schief WR, Batista FD.   +41 more
europepmc   +1 more source

Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation [PDF]

, 2012
Teruhito Yasui, Kaori Sakakibara-Yada, Taki Nishimura, Kentaro Morita, Satoru Tada, George Mosialos, Elliott Kieff, Hitoshi Kikutani   +7 more
openalex   +1 more source