Results 221 to 230 of about 63,576 (258)

The chilling origin of germinal centers

Science Immunology, 2023
Germinal center–like structures have been identified in ectothermic vertebrates, establishing germinal centers as a universal component of humoral immunity (see related Research Article by Shibasaki et al. )
openaire   +5 more sources

To ‘B’ or not to ‘B’ a germinal center?

Immunology Today, 1997
Abstract Under certain pathological conditions, germinal centers (GCs) form in many atypical sites, such as the stomach, lung and synovial joints. Thus, understanding the cellular and molecular interactions leading to a GC response is relevant not only for protective immunity but also for possible therapeutic strategies.
M H, Kosco-Vilbois, H, Zentgraf, J, Gerdes, J Y, Bonnefoy   +3 more
openaire   +2 more sources

Germinal centers develop oligoclonally

European Journal of Immunology, 1987
AbstractAs part of our studies into the role of germinal centers, we investigated whether each de novo generated germinal center (GC) develops from one single GC precursor cell (GCPC, monoclonal development), a few GCPC (oligoclonal development) or from many GCPC (polyclonal development).
Kroese, FGM, Wubbena, AS, Seijen, HG, Nieuwenhuis, P   +3 more
openaire   +3 more sources

Repulsive behavior in germinal centers

Science, 2017
B cell–T cell interactions are terminated by EPH receptors and ...
G. Leandros Moschovakis, Reinhold Förster   +1 more
openaire   +2 more sources

How to Simulate a Germinal Center

2017
Germinal centers host a mini-evolutionary environment where B cells can mutate their receptor and be selected depending on its affinity to target antigens in a process called affinity maturation. Starting from founder cells with a weak B cell receptor affinity, germinal centers release output cells as antibody-secreting cells or memory cells with a ...
Philippe A, Robert, Ananya, Rastogi, Sebastian C, Binder, Michael, Meyer-Hermann   +3 more
openaire   +2 more sources

Continuous germinal center invasion contributes to the diversity of the immune response

Cell, 2023
Charlotte Viant
exaly  

Clonal replacement sustains long-lived germinal centers primed by respiratory viruses

Cell, 2023
Gabriel Victora, Alexandru Barbulescu
exaly  

Interleukin-21, acting beyond the immunological synapse, independently controls T follicular helper and germinal center B cells

Immunity, 2022
Marcus Robinson, Isaak Quast, Zhoujie Ding   +2 more
exaly  

Hypoxic germinal centers

Nature Immunology, 2016
openaire   +2 more sources

Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals

Cell, 2022
Alessandro Sette, Michela Locci, Kavitha Muralidharan   +2 more
exaly