Results 101 to 110 of about 340,349 (250)

Cost-effectiveness of fuzuloparib compared to routine surveillance, niraparib and olaparib for maintenance treatment of patients with germline BRCA1/2 mutation and platinum-sensitive recurrent ovarian carcinoma in China [PDF]

, 2023
Jing Nie, Huina Wu, Lei Sun, Yanjiao Ding, Yepeng Luan, Jiyong Wu   +5 more
openalex   +1 more source

Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine [PDF]

, 2010
Coordination between cell fate specification and cell cycle control in multicellular organisms is essential to regulate cell numbers in tissues and organs during development, and its failure may lead to oncogenesis.
Alexandra Segref, Ashcroft N., Ashcroft N. R., Bao Z., Bei Y., Bischoff M., Boutros R., Boxem M., Busino L., Caroline Clucas, Clucas C., Desai A., Edgar L. G., Fire A., Fraser A. G., Galaktionov K., Goldstein B., Goldstein B., Gregorieff A., Hebeisen M., Iain L. Johnstone, Jin J., Juan Cabello, Kaletta T., Kamath R. S., Kikuchi A., Kipreos E. T., Kipreos E. T., Korswagen H. C., Kostic I., Kristjansdottir K., Lin R., Maduro M. F., Marcos Gonzalez-Gaitan, Nishi Y., Ougolkov A., Pellettieri J., Polakis P., Praitis V., Ralf Schnabel, Rivers D. M., Rocheleau C. E., Rocheleau C. E., Schierenberg E., Schlesinger A., Schnabel R., Shirayama M., Sokal R. R., Sulston J. E., Sulston J. E., Thorpe C. J., Thorpe C. J., Timmons L.   +52 more
core   +2 more sources

Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death. [PDF]

, 2020
Timely sister chromatid separation, promoted by separase, is essential for faithful chromosome segregation. Separase is a member of the CD clan of cysteine proteases, which also includes the pro-apoptotic enzymes known as caspases.
Jeong, Pan Young, Joshi, Pradeep M, Kumar, Ashish, Rothman, Joel H   +3 more
core   +1 more source

An antigen-driven B-cell response within the salivary glands of patients with Sjögren’s syndrome [PDF]

, 2002
Infection with a bacterium or virus induces the production of antibodies, specialised protein molecules that bind to and eliminate the microorganism.
Berek, C., Stott, D.I.
core  

Identification of germline population variants misclassified as cancer-associated somatic variants

Frontiers in Medicine
IntroductionDatabases used for clinical interpretation in oncology rely on genetic data derived primarily from patients of European ancestry, leading to biases in cancer genetics research and clinical practice.
Rebecca D. Pollard, Rebecca D. Pollard, Matthew D. Wilkerson, Matthew D. Wilkerson, Padma Sheila Rajagopal, Padma Sheila Rajagopal   +5 more
doaj   +1 more source

Gender-specific hierarchy in nuage localization of PIWI-interacting RNA factors in Drosophila

Frontiers in Genetics, 2011
PIWI-interacting RNAs (piRNAs) are germline-specific small non-coding RNAs that form piRNA-induced silencing complexes (piRISCs) by associating with PIWI proteins, a subclade of the Argonaute proteins predominantly expressed in the germline.
Mikiko C Siomi, Mikiko C Siomi, Akihiro eNagao, Kaoru eSato, Kazumichi M Nishida, Haruhiko eSiomi   +5 more
doaj   +1 more source

Gremlins in the Germline

The American Journal of Bioethics, 2020
Bryan Cwik shows the importance of asking questions such as: what is goal of a given germline intervention? Does the specific method of intervention have its own idiosyncratic ethical texture? Are there alternative means of producing the same end that are less risky and less morally contentious?
openaire   +2 more sources

Editorial: Germline Development: From Germline Stem Cells to Gametes [PDF]

Frontiers in Cell and Developmental Biology, 2020
Myon-Hee Lee, Rosa E. Navarro, Sung Min Han   +2 more
openaire   +3 more sources

Long-term cultures of murine fetal liver retain very early B lymphoid phenotype. [PDF]

, 1984
Long-term cultures of murine fetal liver have been successfully established using a modification of our in vitro bone marrow culture system (14, 15).
Denis, KA, St Claire, JI, Treiman, LJ, Witte, ON   +3 more
core  

Fine-tuning germline mutation rates across evolution [PDF]

, 2023
Stephen J. Bush, Anne Goriely
openalex   +1 more source