Results 141 to 150 of about 214,576 (214)

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

Exploration, EarlyView.
This study aimed to determine how microbiota compositions (via 16S rRNA sequencing) correlate with clinical outcome and metabolome (via liquid chromatography/mass spectrometry) of CBA. Sputum microbiome and metabolome profiles of CBA were well separated from COPD but not bronchiectasis, partly driven by the higher abundance of Proteobacteria in CBA ...
Zhen‐feng He, Xiao‐xian Zhang, Cui‐xia Pan, Xin‐zhu Yi, Yan Huang, Chun‐lan Chen, Shan‐shan Zha, Lai‐jian Cen, Han‐qin Cai, Lei Yang, Jia‐qi Gao, Hui‐min Li, Zhen‐hong Lin, Sheng‐zhu Lin, Zhang Wang, Nan‐shan Zhong, Wei‐jie Guan   +16 more
wiley   +1 more source

Contrast-enhanced ultrasound assessment of the therapeutic efficacy and treatment of a large renal artery aneurysm following multiple vascular reconstructions: a case description. [PDF]

Quant Imaging Med Surg
Wang Y, Wang Y, Liu R, Ren J.
europepmc   +1 more source

Cancer Immunotherapy Based on the Bidirectional Reprogramming of the Tumor Microenvironment by a “Brakes Off/ Step on the Accelerator” Core‐Shell Manganese Phosphate/siPD‐L1 Modulator

Exploration, EarlyView.
To enhance the comprehensive treatment effect of triple‐negative breast cancer, a pH‐responsive core‐shell manganese phosphate nano‐regulator was prepared to reprogram the tumor microenvironment bi‐directionally. (1) “Brakes off”: Using siPD‐L1 to inhibit PD‐L1 expression to restore CD8+ T cell function.
Fei Xia, Yuqian Lu, Zipeng Gong, Qingchao Tu, Shuntao Liang, Chen Wang, HaiLu Yao, LinYing Zhong, Yuanfeng Fu, Pengbo Guo, Yichong Hou, Xinyu Zhou, Li Zou, Licheng Gan, Weiqi Chen, Jiawei Yan, Junzhe Zhang, Huanhuan Pang, Yuqing Meng, Qiaoli Shi, Chen Pan, Xiaomei Tao, Jigang Wang, Qingfeng Du, Chong Qiu   +24 more
wiley   +1 more source

FABP7 Expression Modulates the Response of Astrocytes to Induced Endotoxemia

Glia, EarlyView.
FABP7 silencing reduces inflammatory response in astrocytes. FABP7 silencing decreases astrocyte‐mediated neurotoxicity. FABP7 silencing attenuates NF‐κB‐dependent transcriptional response during endotoxemia. ABSTRACT Fatty acid binding proteins (FABPs) are a family of small proteins involved in fatty acid (FA) subcellular trafficking.
Mariana Bresque, Daniel Esteve, Garret Balmer, Haylee L. Hamilton, Joshua S. Stephany, Mariana Pehar, Marcelo R. Vargas   +6 more
wiley   +1 more source

Surgical and Medical Co‐Management in an 82‐Year‐Old Patient With Hemophilia a Undergoing Pancreaticoduodenectomy

Health Care Science, EarlyView.
The surgical and medical co‐management (SMC) team integrates internists and surgeons to improve perioperative planning to minimize complications and promote recovery. SMCs team implemented various perioperative optimization strategies for the patient to prevent complications and enhance satisfaction.
Wenning Lu, Chaoyang Liu, Jing He, Rui Cheng   +3 more
wiley   +1 more source

Insights into the interconnection of sarcopenia in heart failure

ESC Heart Failure, EarlyView.
Zhengyang Ge, Yanming Wu, Biao Wang
wiley   +1 more source

Investigating the Spillover Mechanisms of Payment Incentives on the Outcomes for Non‐Targeted Patients

Health Economics, EarlyView.
ABSTRACT Payment reforms in healthcare can have spillover effects on the care experienced by non‐targeted patients treated by the same provider. Few empirical studies have quantitatively investigated the mechanisms behind these effects. We formulate theory‐driven hypotheses to investigate the spillover mechanisms of a regional payment reform in the ...
Philip Britteon, Søren Rud Kristensen, Yiu‐Shing Lau, Ruth McDonald, Matt Sutton   +4 more
wiley   +1 more source

Multidimensional Prognostic Index as a Predictor of Mortality in Head and Neck Cancer Patients: A Cohort Study

Head &Neck, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) significantly impacts older adults, with mortality influenced by multiple factors. The Multidimensional Prognostic Index (MPI), derived from comprehensive geriatric assessment (CGA), may improve risk stratification and clinical decision making. Methods An observational cohort study was conducted at Erasmus
Ajay T. Bakas, Aniel Sewnaik, Femke Flikweert, Robert Jan Baatenburg de Jong, Francesco Mattace‐Raso, Harmke Polinder‐Bos   +5 more
wiley   +1 more source

Reply to comment on "Regional disparities in home health care utilization for older adults and their associated factors at the secondary medical area level: A nationwide study in Japan". [PDF]

Geriatr Gerontol Int
Sun Y, Sakata N, Iwagami M, Yoshie S, Inokuchi R, Ito T, Kuroda N, Hamano J, Tamiya N.   +8 more
europepmc   +1 more source

Strengthening Health Workforce in Georgia: Identifying Gaps and Integrating Evidence‐Based Strategic Planning

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Health workforce planning is essential for ensuring a resilient and well‐functioning healthcare system capable of addressing population needs and responding to crises. In Georgia, an upper‐middle‐income country, significant challenges remain in the strategic planning, regulation, and management of the health workforce.
Giorgi Aladashvili, Mariam Kirvalidze, Aleksandre Tskitishvili, Nikoloz Chelidze, Nikoloz Tvildiani, Giorgi Pkhakadze, Thomas J. Bossert, Karsten Lunze, Ilia Nadareishvili   +8 more
wiley   +1 more source