Results 121 to 130 of about 112,165 (302)

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li   +9 more
wiley   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

open access: yesAdvanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao   +10 more
wiley   +1 more source

Creative Gerontology [PDF]

open access: yes, 2018
Gerontologia kreatywna - dział gerontologii społecznej postulowany przez Anitę Stefańską i Martę Szabelską-Holeksę (2013, s. 155-165). Docelowo subdyscyplina ta ma zajmować się problematyką twórczości i kreatywności osób starszych. Gerontologia kreatywna
Klimczuk, Andrzej
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DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

open access: yesAdvanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang   +8 more
wiley   +1 more source

Overview: Intimate Partner Violence & Rural Older Women

open access: yes, 2010
Intimate partner violence (IPV) is defined as physical, sexual, or psychological abuse by a spouse, boyfriend, or intimate partner. It is a hidden public health problem, touching nearly one third of all women aged 50+ each year.
Center for Gerontology
core  

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

open access: yesAGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang   +3 more
wiley   +1 more source

Helping a Friend/Helping Yourself: Intimate Partner Violence & Rural Older Women

open access: yes, 2010
Intimate Partner Violence (IPV) is physical, emotional, psychological, or sexual abuse by a husband, boyfriend or other intimate partner. IPV may include harsh or cruel criticism, threats of abandonment, intentional isolation from family and friends ...
Center for Gerontology
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Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Implementation of the 2006 Ohio nursing home family satisfaction survey final report

open access: yes, 2007
Title from PDF cover (viewed on Aug. 28, 2007).; "Submitted to The Ohio Department of Aging, March 30, 2007."; "Prepared under contract to the Ohio Department of Aging by the Scripps Gerontology Center, Miami University, Oxford, OH and the Margaret ...
Straker, Jane K.
core  

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