Results 121 to 130 of about 258,068 (311)

The discourse of ageing dynamics in contemporary US drama: definitions and representations [PDF]

open access: yes, 2015
У статті здійснюється спроба визначення літературної геронтології як міждисциплінарної галузі гуманітарного знання. Представлено робочу гіпотезу поняття вікової динаміки старіння в рамках літературної геронтології для аналізу проблемно-семантичних та ...
Гайдаш, Анна Владиславівна
core  

An investigation of factors associated with depression in older adults

open access: yes, 1989
As the population ages, there is a need for continued research into the etiology of geriatric depression and improved ways to detect individuals at risk for developing this disorder.
Mayhew, Katherine Mary
core   +1 more source

T Cell‐Independent Role of PD‐L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD‐L1/BRCA1 Interaction Following AKI

open access: yesAdvanced Science, EarlyView.
PD‐L1 is primarily expressed in renal tubules and upregulated in both murine models of AKI and renal biopsy samples from patients with AKI. PD‐L1 can promote adaptive TECs repair through interacting with BRCA1, independent of its canonical immunomodulatory function of T cells, and PD‐L1 supplementation may represent a promising therapeutic strategy for
Wei Jiang   +17 more
wiley   +1 more source

Editorial: Emotion regulation and mental health in older adults

open access: yesFrontiers in Psychology, 2023
Gary Christopher, David Facal
doaj   +1 more source

AlzHope: A Multi-volume eBook Confidence Builder for Alzheimer’s Worriers

open access: yesNonpartisan Education Review, 2010
no ...
Robert Oliphant
doaj  

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song   +10 more
wiley   +1 more source

Factors Affecting Nursing Students\u27 Attitudes Towards Older Adults [PDF]

open access: yes, 2006
The purpose of this study was to measure nursing students\u27 attitudes towards older adults and to determine, if possible, factors which affect nursing students\u27 attitudes toward older adults.
McCammon, Tracy
core   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

open access: yesAdvanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang   +19 more
wiley   +1 more source

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

open access: yesAdvanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng   +6 more
wiley   +1 more source

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