Results 141 to 150 of about 258,068 (311)

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin   +15 more
wiley   +1 more source

Prevalence and Risk Factors of Fear of Falling among Elderly: A Review [PDF]

open access: yes, 2018
The world population is aging rapidly. Fear of falling among the elderly constitute a significant problem in health care. Among community-dwelling elderly, fear of falling is frequent, with prevalence ranging from
Rahman, Md Sazedur
core  

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

International Journal of Gerontology

open access: yesInternational Journal of Gerontology, 2007
Cheng-Ho Tsai, President, TSGECM   +1 more
doaj   +1 more source

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

open access: yesAGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang   +3 more
wiley   +1 more source

Synthetic MRI Neuroimaging Correlates of Frailty: Correlations Between Frailty Scales and Brain Structural Integrity

open access: yesAGING MEDICINE, EarlyView.
Frailty was associated with decreased gray and white matter brain volumes in older adults. Synthetic MRI further revealed relaxometry alterations correlated with frailty severity across multiple clinical scales. ABSTRACT Objectives Frailty, a common condition in the elderly, is characterized by a decline in physiological reserves and an increased ...
Yuhui Chen   +7 more
wiley   +1 more source

Biomarkers of Sarcopenia: Current Status and Future Perspectives

open access: yesAGING MEDICINE, EarlyView.
In this review, we summarize the various biomarkers discovered in recent years, including biochemical, imaging, and physical testing markers. We analyze their advantages and disadvantages and propose potential ways to improve the diagnostic accuracy of biomarkers, as well as future research directions.
Bijin Luo   +6 more
wiley   +1 more source

Defining Frailty in Chinese‐Language Biomedical Literature (2014–2024): A Decade of Conceptual Evolution

open access: yesAGING MEDICINE, EarlyView.
Frailty definitions in Chinese‐language biomedical literature increasingly align with international frameworks, while retaining conceptual diversity, underscoring the need for multidimensional, cross‐cultural research and integration with traditional Chinese medicine for culturally sensitive clinical practice.
Haodong Wei   +5 more
wiley   +1 more source

Morbidity Among the Aging Population in Northern Bangladesh: An Epidemiological Study

open access: yesAGING MEDICINE, EarlyView.
Multimorbidity (≥ 2 chronic diseases) is common among aging populations, yet evidence from Bangladesh remains limited. A cross‐sectional survey of 540 older adults in Northern Bangladesh (June–August 2022) assessed multimorbidity using interviews and logistic regression analysis. Multimorbidity prevalence was 75.74% (95% CI: 71.9%–79.3%).
Md. Abu Sayem   +3 more
wiley   +1 more source

Potential applications of virtual reality devices in older people. Narrative review

open access: yesJournal of Education, Health and Sport, 2019
Introduction Many of the non-pharmacological therapeutic interventions such as physical and mental exercises are focused on some of the dimensions of human cognition only.
Agnieszka Kujawska   +13 more
doaj  

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