Results 131 to 140 of about 258,068 (311)
Representation of Old Age and Pain in Iris
Adapted for the screen by Sir Richard and Charles Wood and directed by Sir Richard Eyre, Iris tells the life story of famous British philosopher and novelist, Iris Murdoch.
Fatma Kalpaklı
doaj
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan +11 more
wiley +1 more source
Is Gerontology Interdisciplinary? [PDF]
openaire +2 more sources
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin +12 more
wiley +1 more source
Introduction and objective: To evaluate the association between obesity and independent variables in the elderly of a southern city in Brazil. Material and methods: This is a home-based cross-sectional study conducted in 287 elders, aged 65 to 74 years ...
Renata Sebastiana de Souza Pizolotto +6 more
doaj
Raising the level of medical gerontology: Evaluation of the European Academy for Medicine of Ageing course [PDF]
The two-year EAMA course was established in 1995 by the Group of European Professors in Medical Gerontology (GEPMG) with the aim of raising the global standard of medical gerontology in (chiefly) European junior faculties. To determine the impact of this
Michel, J-P
core
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li +8 more
wiley +1 more source
Home accidents amongst elderly people: A locality study in Scotland [PDF]
Aim The aim of this locality study was to collect information on reported and unreported accidents amongst elderly people living in one locality in Scotland.
Banks, P +6 more
core
Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen +15 more
wiley +1 more source

