Results 111 to 120 of about 282,755 (347)

Bilirubin as a Modulator of WNK1 Protein Signaling: Implications for Neuroinflammatory Diseases

open access: yesAdvanced Science, EarlyView.
ABSTRACT Previously regarded merely as a potentially harmful waste product of heme catabolism, bilirubin has now emerged as a pleiotropic molecule with potent antioxidant, anti‐inflammatory, and hormone‐like properties. Recent findings have revealed protective effects against cardiovascular, metabolic, autoimmune, and neoplastic diseases, as well as ...
Sri Jayanti   +3 more
wiley   +1 more source

Ten years of integrated care for the older in France

open access: yesInternational Journal of Integrated Care, 2011
Background: This paper analyzes progress made toward the integration of the French health care system for the older and chronically ill population. Policies: Over the last ten years, the French health care system has been principally influenced by two ...
Dominique Somme, Matthieu de Stampa
doaj   +1 more source

Factors Affecting Nursing Students\u27 Attitudes Towards Older Adults [PDF]

open access: yes, 2006
The purpose of this study was to measure nursing students\u27 attitudes towards older adults and to determine, if possible, factors which affect nursing students\u27 attitudes toward older adults.
McCammon, Tracy
core   +1 more source

Communicating with older ethnic minority patients [PDF]

open access: yes, 2014
In a time of increasing cultural diversity, it is essential that healthcare professionals respond by providing culturally competent care. Healthcare professionals must recognise the diverse needs of people from ethnic minority communities to ensure that ...
Likupe, Gloria
core   +2 more sources

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

open access: yesAdvanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu   +12 more
wiley   +1 more source

Excluded from the Good Life? An Ethical Approach to Conceptions of Active Ageing

open access: yesSocial Inclusion, 2019
Contesting previous deficit-oriented models of ageing by focusing on the resources and potential of older people, concepts of ‘successful’, ‘productive’, and ‘active ageing’ permeate social policy discourses and agendas in ageing societies. They not only
Larissa Pfaller, Mark Schweda
doaj   +1 more source

Listening to Life’s Lessons: Using music Lyrics and Poetry to Face Issues of Aging in the Classroom [PDF]

open access: yes, 2008
The use of poetry and music in college courses on aging is discussed. The format can help instructors reach their students in new ways. Poetry and music can be used to engage students in material that may be emotionally charged.
Weinberger, Nanci
core   +2 more sources

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren   +5 more
wiley   +1 more source

Impact of Multidisciplinary Collaboration on Microbiological Specimen Submission and Appropriate Use of Carbapenems: A Pre-Post Cohort Study

open access: yesInfection and Drug Resistance
Qi Zou,1 Yatong Zhang,2 Xiaoman Ai,3 Xiaoming Tan,4 Xia Wang,5 Ji Luo,6 Meng Cai1 1Department of Infection Control, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People’s ...
Zou Q   +6 more
doaj  

An investigation of factors associated with depression in older adults

open access: yes, 1989
As the population ages, there is a need for continued research into the etiology of geriatric depression and improved ways to detect individuals at risk for developing this disorder.
Mayhew, Katherine Mary
core   +1 more source

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