Results 91 to 100 of about 113,802 (301)

A gerontological statistic.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1998
No ...
openaire   +2 more sources

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Freestanding Hierarchical‐Porous BCZT Thin Films Enable Efficient Ultrasonic Energy Harvesting in Soft Tissue

open access: yesAdvanced Science, EarlyView.
Freestanding hierarchical‐porous BCZT thin films integrate a compliant porous surface with a dense piezoceramic backbone to balance mechanical reliability, voltage sensitivity, and acoustic coupling. The films enable stable wearable pulse‐wave monitoring and enhanced tissue‐coupled ultrasonic energy harvesting, offering a promising route toward soft ...
Zifan Li   +14 more
wiley   +1 more source

Características individuais e clínicas de pessoas idosas com diabetes: investigação temática em oficina sociopoética [Individuals and clinics characteristics of elderly people with diabetes: thematic research in sociopoetic workshop]

open access: yesRevista Enfermagem UERJ, 2013
Este trabalho teve como objetivo delinear o perfil sociodemográfico e clínico de pessoas idosas com diabetes, visando posterior orientação para o autocuidado. Método sociopoético, na etapa de investigação temática entre um grupo pesquisador composto por
Iraci dos Santos   +2 more
doaj  

Probabilistic Estimation of Human Interaction Needs in Context of a Robotic Assistance in Geriatrics

open access: yesCurrent Directions in Biomedical Engineering, 2019
The key purpose of assistance robots is to help people coping with work-related or everyday tasks. To ensure an intuitive and effective support by an assistance robot, its expectation conform behavior is essential.
Philipp Patrick   +3 more
doaj   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

open access: yesAdvanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li   +11 more
wiley   +1 more source

Merging ‘Critical Criminology’ with ‘Critical Gerontology’ [PDF]

open access: yes, 2012
This paper analyses the extent to which aging has been overlooked by ‘critical criminology’. The notion of ‘aging’ is introduced and the paper argues that there are strong conceptual insights from another discipline that Critical Criminology should learn
Powell, Jason
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li   +9 more
wiley   +1 more source

The Present Status of Web-Based Gerontology Education: Challenges and Opportunites in the 21th-Century: Development of an Online Course, Gerontology 2050, Aging: Concepts and Controversies

open access: yes, 2001
The presence of Web-based gerontology courses and programs are growing. This article discusses the number of programs and courses available at colleges and universities in the United States and provides a current database of what is presently available ...
Carlin, Kevin
core  

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