Results 91 to 100 of about 113,802 (301)
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openaire +2 more sources
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang +11 more
wiley +1 more source
Freestanding hierarchical‐porous BCZT thin films integrate a compliant porous surface with a dense piezoceramic backbone to balance mechanical reliability, voltage sensitivity, and acoustic coupling. The films enable stable wearable pulse‐wave monitoring and enhanced tissue‐coupled ultrasonic energy harvesting, offering a promising route toward soft ...
Zifan Li +14 more
wiley +1 more source
Este trabalho teve como objetivo delinear o perfil sociodemográfico e clínico de pessoas idosas com diabetes, visando posterior orientação para o autocuidado. Método sociopoético, na etapa de investigação temática entre um grupo pesquisador composto por
Iraci dos Santos +2 more
doaj
Probabilistic Estimation of Human Interaction Needs in Context of a Robotic Assistance in Geriatrics
The key purpose of assistance robots is to help people coping with work-related or everyday tasks. To ensure an intuitive and effective support by an assistance robot, its expectation conform behavior is essential.
Philipp Patrick +3 more
doaj +1 more source
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Merging ‘Critical Criminology’ with ‘Critical Gerontology’ [PDF]
This paper analyses the extent to which aging has been overlooked by ‘critical criminology’. The notion of ‘aging’ is introduced and the paper argues that there are strong conceptual insights from another discipline that Critical Criminology should learn
Powell, Jason
core +1 more source
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li +9 more
wiley +1 more source
The presence of Web-based gerontology courses and programs are growing. This article discusses the number of programs and courses available at colleges and universities in the United States and provides a current database of what is presently available ...
Carlin, Kevin
core

