Results 81 to 90 of about 113,802 (301)

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

FEATURES AND PROFILE OF ENROLLED IN ELDERLY FAMILY HEALTH PROGRAM [PDF]

open access: yesRevista Gestão & Saúde, 2011
This essay aims to provide brief information about aspects of aging on their influence on functional capacity, not only on the intrinsic factors, such as physiological and disease, but as to extrinsic factors such as socioeconomic and demographic ...
Adriano Drummond
doaj  

Offering Service-Learning in Gerontology Through a Coordinated Curriculum Model

open access: yes, 2001
The purpose of this project was to develop a model for introducing service learning to an entire academic gerontology program curriculum. Brief historical backgrounds of service-learning and of gerontology are provided, along with a discussion of the ...
Murakami, Jacob
core  

Critical educational gerontology : a third statement of first principles [PDF]

open access: yes, 2011
This article elaborates upon the initial statement of first principles for critical educational gerontology [CEG] established by Glendenning and Battersby some two decades ago, whilst taking stock of the body of critique levelled at such principles by ...
Formosa, Marvin
core  

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li   +17 more
wiley   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li   +9 more
wiley   +1 more source

„Mit 70 Jahren hat kein Mensch das Recht, sich alt zu fühlen.“ – Altersdiskurse und Bilder des Alters in der NS-Sozialpolitik

open access: yesÖsterreichische Zeitschrift für Geschichtswissenschaften, 2011
Social policies of Nazi Germany aimed directly at cutting expenses for pensions and other social security benefits for old people. In order to reduce social costs, the age of retirement was supposed to be increased through various policies.
Benjamin Möckel
doaj   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

open access: yesAdvanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang   +10 more
wiley   +1 more source

Female gerontology in TV-advertising [PDF]

open access: yesСоциологический журнал, 2012
The paper backgrounds the necessity of theoretical advancing the female gerontology project. Two models of female gerontology problems interpretation are considered: the model of “mail dominance” and the model of “female narcissism”.
doaj  

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu   +20 more
wiley   +1 more source

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