Results 61 to 70 of about 80,990 (260)

„Mit 70 Jahren hat kein Mensch das Recht, sich alt zu fühlen.“ – Altersdiskurse und Bilder des Alters in der NS-Sozialpolitik

Österreichische Zeitschrift für Geschichtswissenschaften, 2011
Social policies of Nazi Germany aimed directly at cutting expenses for pensions and other social security benefits for old people. In order to reduce social costs, the age of retirement was supposed to be increased through various policies.
Benjamin Möckel
doaj   +1 more source

Frailty is an independent risk factor for recurrence and mortality following curative resection of stage I–III colorectal cancer

Annals of Gastroenterological Surgery, 2020
Aim With population aging, the number of frail patients with colorectal cancer has increased. The Clinical Frailty Scale (CFS) is a validated tool for assessing frailty, and higher scores indicate worse clinical outcomes following cardiovascular ...
Kosuke Mima, Nobutomo Miyanari, Atsushi Morito, Shinsei Yumoto, Takashi Matsumoto, Keisuke Kosumi, Mitsuhiro Inoue, Takao Mizumoto, Tatsuo Kubota, Hideo Baba   +9 more
doaj   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Female gerontology in TV-advertising [PDF]

Социологический журнал, 2012
The paper backgrounds the necessity of theoretical advancing the female gerontology project. Two models of female gerontology problems interpretation are considered: the model of “mail dominance” and the model of “female narcissism”.
doaj  

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Características individuais e clínicas de pessoas idosas com diabetes: investigação temática em oficina sociopoética [Individuals and clinics characteristics of elderly people with diabetes: thematic research in sociopoetic workshop]

Revista Enfermagem UERJ, 2013
Este trabalho teve como objetivo delinear o perfil sociodemográfico e clínico de pessoas idosas com diabetes, visando posterior orientação para o autocuidado. Método sociopoético, na etapa de investigação temática entre um grupo pesquisador composto por
Iraci dos Santos, Renata Gomes Guerra, Leandro Andrade da Silva   +2 more
doaj  

Probabilistic Estimation of Human Interaction Needs in Context of a Robotic Assistance in Geriatrics

Current Directions in Biomedical Engineering, 2019
The key purpose of assistance robots is to help people coping with work-related or everyday tasks. To ensure an intuitive and effective support by an assistance robot, its expectation conform behavior is essential.
Philipp Patrick, Bommersheim Marie, Robert Sebastian, Beyerer Jürgen   +3 more
doaj   +1 more source

Ageing, old age and media: Critical appraisal of knowledge practices in academic research

International Journal of Ageing and Later Life, 2019
This interpretative literature review discusses research published between 2000 and 2015 that focuses on the media representation of older adults. The key objective is to offer a critical discussion on the knowledge and assumptions underlying such ...
Sara Mosberg Iversen, Monika Wilinska
doaj   +1 more source