Results 41 to 50 of about 80,990 (260)
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub +24 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source
The social context of substance use among older adults: Implications for nursing practice
Nursing Open, 2019 Aim The purposes of this paper are (a) to critically analyse the social context of substance use among older adults and (b) to offer strategies for nurses and other health care providers to support the health of older adults experiencing problematic ...
Manpreet Kaur Gill Thandi +1 more
doaj +1 more source
Low-Cost Sensor System Design for In-Home Physical Activity Tracking
IEEE Journal of Translational Engineering in Health and Medicine, 2016 An aging and more sedentary population requires interventions aimed at monitoring physical activity, particularly within the home. This research uses simulation, optimization, and regression analyses to assess the feasibility of using a small number of ...
Siddhartha Nambiar +4 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles +14 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source
Sālmand, 2022 Objectives The current study was conducted to compare the perceptions of aging between young and adolescent individuals. The perception of aging is defined as the individual’s perception of one’s aging in their socio-cultural context.
Mohammad Kahrobaei Kalkhuran Alya +2 more
doaj
The need for orthopedic dental services for the elderly population of Kazakhstan [PDF]
Ķazaķstannyṇ Klinikalyķ MedicinasyObjective: To determine the orthopedic dental status of the elderly population of Kazakhstan using clinical and diagnostic determinants. Methods: The dental status of 708 patients from three institutions in Almaty, Kazakhstan, was recorded using WHO ...
Naziya Kamiyeva +3 more
doaj +1 more source