Results 101 to 110 of about 112,165 (302)

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Impact of Multidisciplinary Collaboration on Microbiological Specimen Submission and Appropriate Use of Carbapenems: A Pre-Post Cohort Study

open access: yesInfection and Drug Resistance
Qi Zou,1 Yatong Zhang,2 Xiaoman Ai,3 Xiaoming Tan,4 Xia Wang,5 Ji Luo,6 Meng Cai1 1Department of Infection Control, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People’s ...
Zou Q   +6 more
doaj  

A pilot study of marketability and job placement of interdisciplinary Gerontology graduates, at the undergraduate level, in semirural areas of Northern California

open access: yes, 2015
The problem that this project seeks to examine is that of multidisciplinary placement and job viability for Gerontology graduates. With the growth of the aging population and the desire to adjust the market to the changing needs of the aging population ...
Elizabeth Margaret Near
core  

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li   +17 more
wiley   +1 more source

The Present Status of Web-Based Gerontology Education: Challenges and Opportunites in the 21th-Century: Development of an Online Course, Gerontology 2050, Aging: Concepts and Controversies

open access: yes, 2001
The presence of Web-based gerontology courses and programs are growing. This article discusses the number of programs and courses available at colleges and universities in the United States and provides a current database of what is presently available ...
Carlin, Kevin
core  

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li   +9 more
wiley   +1 more source

Gerontology [PDF]

open access: yes, 2006
The presented thesis is devoted to the issue of gerontology. In the theoretical part I will define the basic terms of social gerontology and then I will briefly deal with its history and current activities. In the next part I will continue by integrating
Thorovská, Alena
core  

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

open access: yesAdvanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang   +10 more
wiley   +1 more source

Intimate Partner Violence and Rural Older Women IPV Resource List

open access: yes, 2010
A list of academic resources and websites about intimate partner violence.This project was supported by an academic-community partnership award # R03HD059478 from the Eunice Kennedy Shriver NICHD and the NIH Office of the Director (OD) to the Center for ...
Center for Gerontology
core  

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

open access: yesAdvanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen   +14 more
wiley   +1 more source

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