Kidney growth in small-for-gestational-age infants: evidence of early accelerated renal growth [PDF]
Very few data are available on longitudinal renal growth in small for gestational age (SGA) infants born at term. The aim of this prospective study was to estimate comparatively the renal growth in SGA infants and in infants born appropriate for gestational age (AGA) during the first 2 years of life.The study comprised groups of SGA and AGA infants ...
Giapros, V. +5 more
openaire +3 more sources
Background Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration (EGAA) are biomarkers of physiological development and may be affected by the perinatal environment.
Anne K. Bozack +6 more
doaj +1 more source
Social determinants of health (SDoH) are defined as the conditions in which people are born, grow, live, work, and age. The distribution of these conditions is influenced by underlying structural factors and may be linked to adverse pregnancy outcomes ...
Jeliyah Clark +8 more
doaj +1 more source
Epigenetic age and pregnancy outcomes: GrimAge acceleration is associated with shorter gestational length and lower birthweight [PDF]
Abstract Background Advanced biological aging, as measured by epigenetic aging indices, is associated with early mortality and morbidity. Associations between maternal epigenetic aging indices in pregnancy and pregnancy outcomes, namely gestational length and birthweight, have not been assessed.
Kharah M. Ross +5 more
openaire +5 more sources
Background: ‘Epigenetic clocks’ have been developed to accurately predict chronologic gestational age and have been associated with child health outcomes in prior work. Methods: We meta-analysed results from four prospective U.S cohorts investigating the
Ashley Y. Song +11 more
doaj +1 more source
Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next‐generation adult rats [PDF]
ABSTRACT Chronic fetal hypoxia is a common complication observed in human pregnancy, impacting pregnancies across global contexts. Exposure to chronic intrauterine hypoxia has major short‐ and long‐term consequences for offspring health.
Aiken C. E. +9 more
openaire +3 more sources
Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation. [PDF]
Aim: To determine whether dynamic DNA methylation changes in the human placenta can be used to predict gestational age. Materials & methods: Publicly available placental DNA methylation data from 12 studies, together with our own dataset, using Illumina ...
Bianco-Miotto, T. +5 more
core +1 more source
Early infant feeding and adiposity risk: from infancy to adulthood [PDF]
Introduction: Systematic reviews suggest that a longer duration of breast-feeding is associated with a reduction in the risk of later overweight and obesity.
Beilin, L J +10 more
core +2 more sources
A Long-Term Enriched Environment Ameliorates the Accelerated Age-Related Memory Impairment Induced by Gestational Administration of Lipopolysaccharide: Role of Plastic Mitochondrial Quality Control [PDF]
Studies have shown that gestational inflammation accelerates age-related memory impairment in mother mice. An enriched environment (EE) can improve age-related memory impairment, whereas mitochondrial dysfunction has been implicated in the pathogenesis of brain aging.
Zhan-Qiang Zhuang +8 more
openaire +3 more sources
Effect of fetal breathing movements on fetal cardiac hemodynamics [PDF]
__Abstract__ Maximum flow velocity waveforms were studied at atrioventricular and outflow tract level in 12 cases during fetal breathing activity and in 12 cases during fetal apnea matched for maternal and gestational age and maternal parity ...
Mooren, K. (K.) van der +2 more
core +1 more source

