An evolutionary genomic approach to identify genes involved in human birth timing. [PDF]
Coordination of fetal maturation with birth timing is essential for mammalian reproduction. In humans, preterm birth is a disorder of profound global health significance.
Jevon Plunkett +22 more
doaj +1 more source
Early changes in pro-inflammatory cytokine levels in neonates with encephalopathy are associated with remote epilepsy. [PDF]
BackgroundNeonatal seizures are associated with adverse neurologic sequelae including epilepsy in childhood. Here we aim to determine whether levels of cytokines in neonates with brain injury are associated with acute symptomatic seizures or remote ...
Barkovich, A James +6 more
core
Recent studies have suggested that gestational diabetes mellitus (GDM) can accelerate cellular aging in multiple cell types in offspring, but its impact on immune senescence remains uncertain. Our prior study reveals GDM increased the secretion of inflammatory factors by monocytes in offspring. This study discovered the transcriptome characteristics of
Yan Zhang +6 more
openaire +3 more sources
Correlation properties of spontaneous motor activity in healthy infants: a new computer-assisted method to evaluate neurological maturation [PDF]
Qualitative assessment of spontaneous motor activity in early infancy is widely used in clinical practice. It enables the description of maturational changes of motor behavior in both healthy infants and infants who are at risk for later neurological ...
Delgado-Eckert, Edgar +6 more
core
Pre-reproductive parental enriching experiences influence progeny’s developmental trajectories [PDF]
While the positive effects of environmental enrichment (EE) applied after weaning, in adulthood, during aging, or even in the presence of brain damage have been widely described, the transgenerational effects of pre-reproductive EE have been less ...
Berretta, Erica +5 more
core +1 more source
Role of osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand axis in nonalcoholic fatty liver disease [PDF]
Concomitantly with the increase in the prevalences of overweight/obesity, nonalcoholic fatty liver disease (NAFLD) has worldwide become the main cause of chronic liver disease in both adults and children.
Andreoli, Gian Marco +4 more
core +1 more source
Report on an international workshop on kangaroo mother care: lessons learned and a vision for the future. [PDF]
Globally, complications of prematurity are the leading cause of death in children under five. Preterm infants who survive their first month of life are at greater risk for various diseases and impairments in infancy, childhood and later life ...
Amani, A +8 more
core +2 more sources
Prenatal prediction of neonatal haemodynamic adaptation after maternal hyperoxygenation
The reactivity of the pulmonary vascular bed to the administration of oxygen is well established in the post-natal circulation. The vasoreactivity demonstrated by the fetal pulmonary artery Doppler waveform in response to maternal hyperoxia has been ...
Ann McHugh +5 more
doaj +1 more source
Whether prenatal exposure to per- and polyfluoroalkyl substances (PFAS) is a risk factor for small-for-gestational-age (SGA) neonates remain elusive, yet even less is known on the role of premature placental aging in this potential adverse effect. In this analysis of 1046 maternal-infant dyads, 30 legacy and emerging PFAS were measured from maternal ...
Yijun Fan +13 more
openaire +3 more sources
Evaluation of the Acceleration and Deceleration Phase-Rectified Slope to Detect and Improve IUGR Clinical Management [PDF]
Objective. This study used a new method called Acceleration (or Deceleration) Phase-Rectified Slope, APRS (or DPRS) to analyze computerized Cardiotocographic (cCTG) traces in intrauterine growth restriction (IUGR), in order to calculate acceleration- and
Andrea Fanelli, * +7 more
core +1 more source

