Results 121 to 130 of about 14,450 (233)
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo +6 more
wiley +1 more source
ABSTRACT Preeclampsia is a severe gestational complication whose molecular pathogenesis remains poorly understood despite extensive research. It is now recognized that both maternal and fetal cells contribute to disease progression. Notably, single‐cell RNA sequencing of cord blood cells from preeclamptic pregnancies has not been previously ...
Polina Vishnyakova +14 more
wiley +1 more source
Gestational Trophoblastic Neoplasia in the 1990s [PDF]
Major advances have been achieved during the past 40 years in the epidemiology, etiology, pathology, endocrinology, immunology, diagnosis, and treatment of molar pregnancy (MP) and gestational trophoblastic neoplasia (GTN).
Goldstein, Donald Peter
core
Generation of Cloned Sheep Lacking Galactose‐α1,3‐Galactose and N‐Glycolylneuraminic Acid Antigens
ABSTRACT Livestock have long been regarded as a potential source of donor organs to alleviate the global organ shortage for transplantation. Sheep have a similar anatomy to humans, providing the standard model for demonstrating biocompatibility and performance of biological heart valves to obtain regulatory approval for their use in transplantation ...
Sarah J. Appleby +9 more
wiley +1 more source
Gestational trophoblastic disease originates from abnormal proliferation of molar tissue and most of them are not complicated. However, life threatening complications such as hyperthyroidism and severe pre-eclampsia can occur.
Raviwon Atisook
doaj
An update on pacemaking in the myometrium
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley +1 more source
Anaesthetic Challenges in Molar Pregnancy
Gestational Trophoblastic Disease (GTD) is a spectrum of tumours with a wide range of biologic behaviour and potential for metastases, which were often fatal in the past.
Ghansham Biyani +2 more
doaj
Identification and Validation of DLD as a Cuproptosis‐Associated Biomarker in Preeclampsia
DLD is identified as a preeclampsia‐associated cuproptosis hub gene by bioinformatics. DLD overexpression inhibits trophoblast proliferation, invasion, and migration, disrupts TCA cycle metabolism, and alters mitochondrial ultrastructure. These findings reveal that DLD may contribute to preeclampsia pathogenesis through cuproptosis.
Shuisen Zheng +4 more
wiley +1 more source
Comparison of ?-HCG Regression Curve in Molar Pregnancy and Gestational Trophoblastic Neoplasms
Introduction & Objective: All cases of gestational trophoblastic tumors are curable if exact diagnosis and early treatment is done. The serum level of βHCG is a sensitive marker of the disease.
Fatemeh Homaee +4 more
doaj
Choriocarcinoma is a rare and aggressive form of gestational trophoblastic disease with a high potential for metastasis. We report the case of a 31-year-old female who presented with severe headaches, left-sided weakness, and speech difficulties.
Bakar Ali Adam, MD +10 more
doaj +1 more source

