Results 101 to 110 of about 7,868 (215)

Thromboinflammatory biomarkers in obstetric pathophysiology: Predictive insights into placental insufficiency and feto‐maternal adverse outcomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Gestational Trophoblastic Disease with Coexisting Progressing Pregnancy: Personalised Treatment Modalities. [PDF]

Int J Clin Pract, 2023
Ulrikh E, Dikareva E, Govorov I, Komlichenko E, Pervunina T, Li O, Zhamborova O, Dzharbaeva A, Deynega V, Artemenko V, Urmancheeva A.   +10 more
europepmc   +1 more source

Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution

iMeta, Volume 5, Issue 4, August 2026.
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang, Hongli Zhao, Xinyi Ding, Haoling Zhang, Yadong Guo, Yiming Ma, Lingyi Cai, Qingnan Fan, Ruisi Peng, Fuyuan Yang, Doblin Sandai, Xianling Cao, Jiali Yao, Wenyi Wang, Zhiheng Lin, Wangzheqi Zhang, Jialin He, Aihua Zhang, Xiaoxuan Zhao   +18 more
wiley   +1 more source

Maternal and infant gut microbiome

iMeta, Volume 5, Issue 4, August 2026.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley   +1 more source

In Vivo Assessment of Placental Structure and Perfusion in Late‐Gestation Pregnancies and Their Association With Fetal Growth

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Multiparametric 3T MRI combining structural imaging and pCASL quantified placental structure and perfusion in late gestation. Mean placental‐blood‐flow (PBF) and arterial‐transit‐time (ATT) values were higher than previously reported at earlier gestational‐ages (GA).
Daphna Link‐Sourani, Netanell Avisdris, Xingfeng Shao, Dana Schonberger, Aviad Rabinowich, Bella Spector Fadida, Yair Wexler, Leo Joskowicz, Liat Ben Sira, Liran Hiersch, Danny J. J. Wang, Dafna Ben Bashat   +11 more
wiley   +1 more source

Maternal High Fat Diet and Acute Viral Mimic Exposure Impact Placental Inflammation, Lipid Peroxidation and Cellular Proliferation‐to‐Death Ratio Across Mouse Pregnancy

American Journal of Reproductive Immunology, Volume 96, Issue 2, August 2026.
Abstract Problem Maternal obesity and viral infection induce placental inflammation, but how their co‐exposure influence fetoplacental development remains unclear. We hypothesised that maternal high fat (HF) diet and viral infection would independently induce placental inflammation and lipid peroxidation, reduce antioxidant defence, and cellular ...
Thaina Ferraz, Lucas Cardoso, Sadra Mohammadkhani, Enrrico Bloise, Kristin L. Connor   +4 more
wiley   +1 more source

Altered Distribution of CD14+ Macrophages and Reduced ROS Activity in Preeclamptic Placentas

American Journal of Reproductive Immunology, Volume 96, Issue 2, August 2026.
ABSTRACT Problem Pregnancy requires a delicate balance between maternal immune tolerance and protective responses, with macrophages playing a pivotal role in placental development and immune regulation. Preeclampsia, a hypertensive disorder that affects 5%–8% of pregnancies, is associated with immune dysregulation, oxidative stress, and impaired ...
Luis Donis‐Maturano, Judith Yenny Flores‐Colque, Juana Calderon‐Amador, Nidia Carolina Moreno‐Corona, Oziel David Pérez‐Luna, Orestes López‐Ortega   +5 more
wiley   +1 more source

PD-L1 in gestational trophoblastic disease: an antibody evaluation. [PDF]

Acta Obstet Gynecol Scand, 2022
Hoeijmakers YM, Simons M, Bulten J, Gorris MAJ, Ottevanger PB, de Vries IJM, Sweep FCGJ.   +6 more
europepmc   +1 more source