Results 81 to 90 of about 7,868 (215)

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar, Purbasa Dasgupta, Soma Ray, Soumen Paul   +3 more
wiley   +1 more source

Unusual Site of Metastasis of Placental Site Trophoblastic Tumor: Case Report and Literature Review

Middle East Journal of Cancer, 2018
Placental site trophoblastic tumor is a subtype of gestational trophoblastic neoplasm with unpredictable clinical behavior. Cytoreductive surgery is the cornerstone of treatment.
Leila Mousavi Seresht, Hamed Golmohamadzadeh, Zohreh Yousefi, Amir Hosein Jafarian, Ali Moghimi, Mojgan Soltani   +5 more
doaj  

Prevotella loescheii attenuates pregnancy‐induced hypertension by reshaping placental immunity and halting macrophage pyroptosis

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Prevotella loescheii alleviates pregnancy‐induced hypertension (PIH) by reshaping the placental immune microenvironment, suppressing oxidative stress (OS)‐mediated NLRP3 pyroptosis, and restoring short‐chain fatty acid (SCFA) metabolic homeostasis. P. loescheii alleviates PIH by reshaping the placental immune microenvironment, suppressing OS‐mediated ...
Jingjing Wu, Linlin Hu, Peipei Chen, Lihong Cai   +3 more
wiley   +1 more source

Predictive Value for Preeclampsia of sFlt‐1:PlGF Ratio in Pregnancy Complicated by Gestational Diabetes

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Background and Aims Gestational diabetes (GDM) and preeclampsia (PE) are major complications of pregnancy. The ratio of soluble Fms‐like tyrosine kinase 1 to placental growth factor (sFlt‐1/PlGF) may predict the short‐term absence of PE in pregnant women with clinically suspected PE. The aim of this study was to determine the role of placental
Fabrizia Citro, Cristina Bianchi, Francesca Nicolì, Michele Aragona, Giovanni De Gennaro, Stefano Del Prato, Giuseppe Penno, Alessandra Bertolotto, Lorella Battini   +8 more
wiley   +1 more source

FIGO staging for gestational trophoblastic neoplasia: 2026

International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1172-1180, September 2026.
Abstract Gestational trophoblastic neoplasia (GTN) encompasses a wide range of diseases, which include choriocarcinoma, placental site trophoblastic tumor, epithelioid trophoblastic tumor, and post‐molar persistent or rising levels of human chorionic gonadotrophin.
Hextan Y. S. Ngan, Michael J. Seckl, Neil Horowitz, Annie N. Y. Cheung, Antonio Braga, Paradan K. Sekharan, Susanne Fridsten, Andrea Garrett, Nozomu Yanaihara, Sarikapan Wilailak, Barbara Schmalfeldt   +10 more
wiley   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

RICTOR Prevents Decidualization Disorder in Women With Advanced Maternal Age via Regulating FoxO1 Nuclear Export

Aging Cell, Volume 25, Issue 9, September 2026.
Advanced maternal age impairs uterine decidualization via downregulated RICTOR‐ATK3‐FoxO1 signaling. The RICTOR agonist MHY1485 rescues decidual defects, offering a therapy for age‐related pregnancy failure. ABSTRACT Miscarriage and abnormal embryonic development in women of advanced maternal age (AMA) are often associated with impaired decidualization.
Yifeng Lin, Jiwei Sun, Yue Ying, Dan Li, Yuewen Ying, Xilin Shen, Xiao Sun, Dan Zhang, Yiqing Wu, Runju Zhang   +9 more
wiley   +1 more source

Guidance for Specialised Cancer Nursing of People With Gynaecological Cancers: A Scoping Review

Journal of Clinical Nursing, Volume 35, Issue 9, Page 3636-3649, September 2026.
ABSTRACT Background Gynaecological cancer nurses are crucial to the delivery of quality, specialised care to meet the needs of people with these cancers. The extent of evidence‐based guidance to support nursing care is unknown. Aim To identify and describe existing international guidance for specialised gynaecological cancer nursing care.
Natalie Williams, Georgia Halkett, Tracey Moroney, Sharon MacLean, Olivia Cook   +4 more
wiley   +1 more source

Actinomycin Derivatives: Structural Diversification and Biological Activities

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, Volume 600, Issue 16, Page 2226-2247, August 2026.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source