Results 91 to 100 of about 7,868 (215)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, Volume 13, Issue 45, 13 August 2026.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Anaesthetic Challenges in Molar Pregnancy

The Indian Anaesthetists' Forum, 2013
Gestational Trophoblastic Disease (GTD) is a spectrum of tumours with a wide range of biologic behaviour and potential for metastases, which were often fatal in the past.
Ghansham Biyani, Sadik Mohammed, Pradeep Bhatia   +2 more
doaj  

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, Volume 101, Issue 4, Page 1627-1640, August 2026.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

Gestational Trophoblastic Disease with Hyperthyroidism and Severe Pre-eclampsia: Anesthetic Management

Siriraj Medical Journal, 2015
Gestational trophoblastic disease originates from abnormal proliferation of molar tissue and most of them are not complicated. However, life threatening complications such as hyperthyroidism and severe pre-eclampsia can occur.
Raviwon Atisook
doaj  

The Immuno‐Cardiovascular Storm of Pre‐Eclampsia: Cytokine‐Mediated Endothelial Injury, Thrombosis, and Maternal Cardiovascular Instability

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Placental ischemia in pre‐eclampsia initiates cytokine‐driven endothelial dysfunction, angiogenic imbalance, oxidative stress, and thromboinflammation. Elevated TNF‐α, IL‐6, IL‐17, sFlt‐1, and complement activation promote vasoconstriction, thrombosis, and cardiovascular instability.
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Comparison of ?-HCG Regression Curve in Molar Pregnancy and Gestational Trophoblastic Neoplasms

پزشکی بالینی ابن سینا, 2011
Introduction & Objective: All cases of gestational trophoblastic tumors are curable if exact diagnosis and early treatment is done. The serum level of βHCG is a sensitive marker of the disease.
Fatemeh Homaee, Maliheh Hassanzadeh, Zohreh Yousefi, Monavar Afzalaghaiee, Ali Yousefi   +4 more
doaj  

Outcomes of Gestational Trophoblastic Disease Management: A Single Centre Review. [PDF]

Medicina (Kaunas), 2023
Malovrh EP, Lukinovič N, Sobočan M, Knez J.   +3 more
europepmc   +1 more source

Erythropoietin Disequilibrium in Hypertensive Disorders of Pregnancy: Molecular Crosstalk, Placental Hypoxia and Perinatal Consequences

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Placental hypoxia, HIF‐1α activation, renal HIF‐2α‐mediated EPO signaling, inflammation, and hepcidin‐driven iron restriction converge to produce functional EPO resistance. This erythropoietin disequilibrium impairs effective erythropoiesis, aggravates maternal vascular dysfunction, compromises placental oxygen transfer, and contributes to adverse ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

“Colon”ised by the unexpected: a case of extrauterine epithelioid trophoblastic tumour

Diagnostic Pathology
Introduction Extrauterine epithelioid trophoblastic tumour is an exceedingly rare and aggressive form of gestational trophoblastic disease that arises outside the uterus and is characterised by the proliferation of intermediate trophoblastic cells ...
Shalini Radhakrishnan, Nischitha N. Suvarna, Saraswathy Sreeram, Srirama Bhat   +3 more
doaj   +1 more source