Results 141 to 150 of about 7,713 (194)

Gestational trophoblastic disease: an update

Abdominal Radiology, 2023
Gestational trophoblastic diseases (GTD) encompass a spectrum of rare pre-malignant and malignant entities originating from trophoblastic tissue. This updated review will highlight important radiological features, pathology and classification, and provide insight into the clinical management of these uncommon disorders.
Tanya Chawla, Genevieve Bouchard-Fortier, Gulisa Turashvili, Ray Osborne, Kalesha Hack, Phyllis Glanc   +5 more
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Gestational trophoblastic diseases

International Journal of Gynecology & Obstetrics, 2003
In 1991, FIGO added non-surgical-pathologic prognostic risk factors to the classic anatomical staging system. These include urinary hCG levels >100000mIU/ml and/or serum b-hCG >40000mIU/ml and the duration of an antecedent pregnancy being >6 months. Since gestational trophoblastic diseases (GTD) have a very high cure rate in virtually all patients, the
Ngan, H. Y, ODICINO, Franco, Maisonneuve, P, Beller, U, Benedet, J. L, Heintz, A. P, PECORELLI, Sergio, Creasman, W. T.   +7 more
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Gestational Trophoblastic Disease

Current Treatment Options in Oncology, 2000
Patients diagnosed with molar pregnancy are treated by either suction curettage or hysterectomy, depending on their desire to preserve fertility. We use single-agent chemotherapy, preferably methotrexate, to treat low- or moderate-risk persistent trophoblastic tumors. High-risk patients who have metastatic disease are treated primarily with combination
J O, Schorge, D P, Goldstein, M R, Bernstein, R S, Berkowitz   +3 more
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GESTATIONAL TROPHOBLASTIC DISEASE

Obstetrics and Gynecology Clinics of North America, 2001
Gestational trophoblastic disease consists of a broad spectrum of conditions ranging from an uncomplicated partial hydatidiform molar pregnancy to stage IV choriocarcinoma with cerebral metastases. Fortunately, with the advent of combination chemotherapy, the patient with advanced-stage disease has a significant chance of achieving complete remission ...
A P, Shapter, R, McLellan
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Gestational Trophoblastic Disease

Radiologic Clinics of North America, 2013
Imaging plays a crucial role in diagnosis and management of gestational trophoblastic disease. Ultrasonography is the initial investigation of choice for the diagnosis. Pelvic magnetic resonance (MR) imaging is used as a problem-solving tool for assessment of degree of local invasion.
Alampady K P, Shanbhogue, Neeraj, Lalwani, Christine O, Menias   +2 more
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Gestational trophoblastic disease

Best Practice & Research Clinical Obstetrics & Gynaecology, 2012
Most women with gestational trophoblastic disease are of reproductive age. Because the disease is readily treatable with favourable prognosis, fertility becomes an important issue. Hydatidiform mole is a relatively benign disease, and most women do not require chemotherapy after uterine evacuation.
Ngan, HYS, Tse, KY
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Gestational Trophoblastic Disease

Clinical Obstetrics and Gynecology, 2007
Hydatidiform mole, a disorder of fertilization, comprises complete and partial molar pregnancy. The pathologic and clinical features of complete and partial mole are well-described. Because of earlier diagnosis, however, the clinical presentation of complete molar pregnancy has significantly changed in recent years.
Elizabeth I O, Garner, Donald P, Goldstein, Colleen M, Feltmate, Ross S, Berkowitz   +3 more
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Gestational Trophoblastic Disease: An Overview

Journal of Midwifery & Women's Health, 2012
This article reviews the different disease entities that fall under the classification of gestational trophoblastic disease (GTD). The conditions included range from molar pregnancy to the malignant forms of gestational trophoblastic neoplasm (GTN). These disorders all arise from abnormal placental trophoblastic development. The different types of GTD,
Ruth, Monchek, Susan, Wiedaseck
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Gestational Trophoblastic Disease

Obstetrics & Gynecology, 2006
This review summarizes the primary management of molar pregnancies, surveillance after evacuation, and the evaluation and management of malignant gestational trophoblastic neoplasia (GTN). Most women with gestational trophoblastic disease can be successfully managed with preservation of their normal reproductive function.
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Nonmetastatic Gestational Trophoblastic Disease

Obstetrics and Gynecology Clinics of North America, 1988
Nonmetastatic gestational trophoblastic disease encompasses a variety of related neoplasms of the human placenta. With the advent of effective chemotherapy, nearly all of these patients can be cured using a variety of regimens with acceptable toxicity.
J T, Soper, C B, Hammond
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