Results 121 to 130 of about 120,747 (306)

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Iba1+ mitotic microglia do not express GFAP.

, 2013
Images show Z-stack projection images taken in the E80 macaque occipital cortex immunostained for PH3 (blue), Iba1 (green) and GFAP (red). Inset panels below show immunoreactivity for each individual antibody.
Verónica Martínez-Cerdeño (155789), Christopher L. Cunningham (187769), Stephen C. Noctor (187793)   +2 more
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Expression of GFAP by NT2-astrocyte cultures.

, 2013
GFAP and vimentin expression in NT2 astrocytes. Images show the varied morphology of the (a) GFAP and (b) vimentin stained NT2 astrocytes. Most are strongly positive for GFAP staining, with some having highly pronounced intermediate-filament structures
Catherine Elizabeth Angel (499909), Jessica Costa (499908), E. Scott Graham (452758), Dan Ting Kho (499907), Christa van Kralingen (499906)   +4 more
core   +1 more source

Structure and Transcriptional Regulation of the GFAP Gene

Brain Pathology, 1994
Transcriptional regulation of the GFAP gene is intimately connected with astrocyte function: its initial activation marks the differentiation of astrocytes, and its up‐regulation accompanies the reactive response to CNS injury. Studies of GFAP transcription should thus provide insights into multiple regulatory pathways operating in these cells.
openaire   +2 more sources

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

p62 in Gfap^+/R236H mice colocalizes with Gfap aggregates and is reduced with loss of Nrf2.

, 2013
(A) p62 immunohistochemistry in hippocampus from Gfap+/R236H/Nrf2+/+ mice shows astrocytic cells that are not apparent in Gfap+/+ mice. Gfap+/R236H/Nrf2−/− mice show similarly stained cells (3 mos of age).
Emily M. Jobe (102132), Albee Messing (320554), Tracy L. Hagemann (320553)   +2 more
core   +1 more source

Müller cell markers in aqueous humor of patients with type-2 macular telangiectasia

Indian Journal of Ophthalmology
Purpose: To investigate the pathogenesis of type-2 macular telangiectasia (MacTel) by comparing the levels of glial fibrillary acidic protein (GFAP), aquaporin-4 (AQP4), and K+ inwardly rectifying channel 4.1 (Kir4.1) in the aqueous humor of diagnosed ...
Elçin Osmanlı, Sabahattin Sül, Ahmet Kaderli, Sema Tamer Kaderli, Ümmühani Türkçü   +4 more
doaj   +1 more source

Solid Ethanol as a Renewable, Low‐Toxicity, Electron‐Beam Direct Write, and Biomedical Material

Advanced Science, EarlyView.
3D ice lithography (3DIL) enables the fabrication of intricate submicrometer objects using ethanol as a renewable starting material. This study combines process optimization, structural and material analysis, and biomedical applications, from cell culture scaffolds to the patterning of neurostimulation electrodes, demonstrating performance in both in ...
Bruno Perdigão, Bingdong Chang, Gwendoline A. E. Anand, Lechan Tao, Kayeon Kim, Anne Zebitz Eriksen, Malte Alexander Schönhoff, Guilherme Ferreira, Xiyuan Liu, Su Genelioglu, Joachim Lyngholm‐Kjærby, Neha Zahoor, Johan Ulrik Lind, Alice Bastos da Silva Fanta, Thomas Willum Hansen, Changsi Cai, Anpan Han   +16 more
wiley   +1 more source

Expression of Acidic Fibrillar Protein and Neuroglobin in Thrombolytic Patients in Ischemic Stroke

Clinical Interventions in Aging
Hanna Pawluk,1 Renata Kołodziejska,1 Grzegorz Grześk,2 Mariusz Kozakiewicz,3 Agnieszka Kosinska,4 Mateusz Pawluk,1 Elżbieta Grzechowiak,5 Jakub Wojtasik,6 Grzegorz Kozera7 1Department of Medical Biology and Biochemistry, Faculty of ...
Pawluk H, Kołodziejska R, Grześk G, Kozakiewicz M, Kosinska A, Pawluk M, Grzechowiak E, Wojtasik J, Kozera G   +8 more
doaj