Results 111 to 120 of about 120,747 (306)

Prognostic biomarkers of recovery from traumatic brain injury: assessment of effectiveness and prospects of application

Якутский медицинский журнал
A literature review was conducted on biomarkers, such as proteins, metabolites and other biological molecules found in biological fluids, as a tool that can improve the understanding of pathophysiological processes in traumatic brain injury (TBI) and ...
I. Sh. Kurbanaliev, M. V. Jalilov, A. A. Genzheeva, A. M. Magaramov   +3 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Glial Fibrillary Acidic Protein (GFAP): Neuroinflammation Biomarker in Acute Ischemic Stroke

Journal of Inflammation Research, 2021
Lisda Amalia Department of Neurology, The First Affiliated Hospital of Faculty of Medicine, Universitas Padjadjaran/RSUP dr. Hasan Sadikin, Bandung, IndonesiaCorrespondence: Lisda Amalia Jl.Pasteur 38, Bandung, 40161, IndonesiaEmail dr.lisda@gmail ...
Amalia L
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THE INFLUENCE OF SAMPLING TIME TO SERUM GLIAL FIBRILLARY ACIDIC PROTEIN (GFAP) LEVELS IN ACUTE STROKE

Malang Neurology Journal, 2019
Background: Serum Glial Fibrillary Acidic Protein (GFAP) is a great potential for biomarker that is widely studied as a diagnostic biomarker of acute stroke.
Neila Raisa, Hidayat Sujuti, Masruroh Rahayu, Mochamad Dalhar   +3 more
doaj   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Neuron-like staining by different GFAP antibodies.

, 2013
Neuron-like structures are stained by the GFAP+1 (A), GFAP C-terminal (B) and GFAP N-terminal (C) antibody (arrows). The C-terminal and N-terminal antibodies also stain astrocytes (B–C, arrowheads).
Dave Speijer (369493), Simone A. van den Berge (369492), Jinte Middeldorp (110012), Elly M. Hol (82147), Eleonora Aronica (135729)   +4 more
core   +1 more source

Magnetic Resonance Imaging Characteristics of Autoimmune Glial Fibrillary Acidic Protein (GFAP) Astrocytopathy: A Pediatric Series in Southwest China

Neuropsychiatric Disease and Treatment, 2023
Weiqin Cheng,1 Ling He,1 Hechuan Luo,1 Yan Jiang,2 Chengbing Tan,2 Xiao Fan1 1Department of Radiology, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key ...
Cheng W, He L, Luo H, Jiang Y, Tan C, Fan X   +5 more
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Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Integration of proteomics and bioinformatics in traumatic brain injury biomarker discovery

BioTechnologia
Background Traumatic brain injury (TBI) is a significant medical crisis with no FDA-approved therapies to improve functional outcomes. Key biomarkers, such as glial fibrillary acidic protein (GFAP), S-100 calcium-binding protein B (S-100B), and ubiquitin
Mohamed M. Mohamed, El-Sayed A. El-Absawy, Hala M. Ahmed, Mohamed E. Hasan   +3 more
doaj   +1 more source

Pathology and Astrocytes in Autism

Neuropsychiatric Disease and Treatment, 2023
Gelareh Vakilzadeh,1,2 Veronica Martinez-Cerdeño1– 3 1Department of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA, USA; 2Institute for Pediatric Regenerative Medicine, and Shriners Hospitals for Children, Sacramento, CA ...
Vakilzadeh G, Martinez-Cerdeño V
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