Results 201 to 210 of about 120,747 (306)

Elevated Serum Neurofilament Light Chain Is Associated With Systemic Inflammation in Very Preterm Infants

Acta Paediatrica, EarlyView.
ABSTRACT Aim Neurofilament light chain (NFL) and glial fibrillary acidic protein (GFAP) are known biomarkers of brain injury in adults, but their significance in very preterm (VPT) infants remains unclear. Given the strong link between inflammation, oxidative stress, and brain injury in this population, we investigated associations between NFL, GFAP ...
E.‐V. Kivivuori, S.‐K. Herukka, S. Kärkkäinen, T. Kokkola, J. Kirjavainen, U. Sankilampi   +5 more
wiley   +1 more source

GFAP im Liquor [PDF]

, 2019
openaire   +1 more source

Elevated Plasma Phospho‐Tau217 in Beta‐Propeller Protein‐Associated Neurodegeneration

Movement Disorders, EarlyView.
Jae‐Hyeok Lee, Yun Soo Kim
wiley   +1 more source

Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease

Brain Pathology, EarlyView.
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

Clinical and molecular features of primary gliosarcoma with digital spatial whole‐transcriptome analysis of glial and mesenchymal components

Brain Pathology, EarlyView.
We report the clinical and genetic features of an institutional cohort of primary adult gliosarcomas compared to glioblastoma. We performed spatial whole‐transcriptome analysis on glial and sarcomatous regions of four cases to compare gene expression profiles and validated differential protein expression for two markers in tissue sections.
Matthew D. Wood, Gabriel Zangirolani, Jinho Lee, Melanie H. Hakar, Tanaya Neff, Kevin Y. Zhang, Christopher L. Corless   +6 more
wiley   +1 more source

Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes. [PDF]

Glia
Zarei-Kheirabadi M, Tyc KM, Dain L, Kheirabadi MA, Hanco J, Mockenhaupt K, Munir S, McQuiston A, Singh SK, Kordula T.   +9 more
europepmc   +1 more source

Quantitative Assessment of GFAP-Based Astrocyte Morphology in the Cuprizone Model: A Comparative Evaluation of Neurolucida^® 360 and SNT. [PDF]

Cells
Wenzel L, Heinig L, Wang D, Vankriekelsvenne E, Wigger N, Zimmermann A, Rößler J, Clarner T, Kipp M.   +8 more
europepmc   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Temporal dynamics of diffusion kurtosis imaging parallels astroglial GFAP expression in a non-traumatic spinal cord injury animal model of ischemia-reperfusion. [PDF]

Front Neurol
Wang L, Li X, Wang L, Li D.
europepmc   +1 more source