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GFAP positivity in neurons following traumatic brain injuries
Glial fibrillary acidic protein (GFAP) is a well-established astrocytic biomarker for the diagnosis, monitoring and outcome prediction of traumatic brain injury (TBI). Few studies stated an accumulation of neuronal GFAP that was observed in various brain
Trautz, Florian +7 more
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The Predictive Role of Neurobiochemical Markers in Multiple Sclerosis
Introduction:Multiple sclerosis (MS) is the most common, chronic, inflammatory, demyelinating disease of the central nervous system. We aimed to evaluate the levels of some neurobiochemical markers in order to evaluate their predictive role in MS.Methods:
Esra Fırat Oğuz +4 more
doaj +1 more source
One of the most remarkable characteristics of astrocytes is their vigorous response to diverse neurologic insults, a feature that is well conserved across a variety of different species. The astroglial response occurs rapidly and can be detected within one hour of a focal mechanical trauma (Mucke et al., 1991).
L F, Eng, R S, Ghirnikar
openaire +2 more sources
Pilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis.
Siddhi Gaurish Sinai Khandeparkar +3 more
doaj +1 more source
Hippocampal Astrocyte Response to Melatonin Following Neural Damage Induction in Rats
Introduction: Brain injury induces an almost immediate response from glial cells, especially astrocytes. Activation of astrocytes leads to the production of inflammatory cytokines and reactive oxygen species that may result in secondary neuronal damage ...
Abdolreza Babaee +5 more
doaj
Immunohistochemical analysis of GFAP expression in the experimental sepsis-associated encephalopathy
Pathophysiology of sepsis-associated encephalopathy (SAE) is linked to blood-brain barrier breakdown, neuroinflammation and neurotransmitter imbalance in the brain. Astroglia, the most abundant cell population within the brain, plays the critical role in
T. V. Shulyatnikova, V. O. Tumaskyi
doaj +1 more source
Marcio Carneiro Vieira,1,2 Fernanda Bezerra de Mello Monte,3 Bruno Eduardo Dematte,3 Tadeu Lima Montagnoli,3 Guilherme Carneiro Montes,3 Jaqueline Soares da Silva,3 Rosalia Mendez-Otero,4 Margarete Manhães Trachez,3 Roberto Takashi Sudo,1,3 Gisele
Vieira M C +9 more
doaj
Objective: the aim of our work is to describe a condition of the reactive astrocytes in the white matter in preterm and term infants with infectious diseases.Materials and methods: postmortem investigation of periventricular white matter performed on ...
S. V. Barashkova
doaj +1 more source
Background: The occurrence of ischemia causes a loss of energy to switch to anaerobic processes resulting in acidosis due to reduced Adenosina Triphosphate (ATP). This condition makes neuron cells apoptotic. Apoptotic of several biochemical substrates in
Diah Retno Wahyuningrum +2 more
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Microstructure white matter changes and serum GFAP among different phenotypes of multiple sclerosis [PDF]
Background. Multiple sclerosis (MS) is an autoimmune disease that targets the central nervous system (CNS). A patient’s degree of demyelination and axonal degeneration can only be roughly estimated based on clinical symptoms, neurochemical analysis or ...
Elsayed Orief +3 more
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