Results 141 to 150 of about 47,706 (229)

THE METABOLIC DISORDER OF ALZHEIMER’S DISEASE IN THE 5XFAD MOUSE MODEL AND HOW INSULIN AND GHRELIN CAN BE USED AS THERAPEUTICS

open access: yes
A subset of patients with Alzheimer’s disease exhibit involuntary age-related weight loss not related to failure to eat. This weight loss can reduce the quality of life, increase frailty, and mortality.
Gendron, William
core  

A Systematic Review and Meta‐Analysis of Perioperative Muscle Wasting Following Major Abdominal Surgery

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Muscle wasting in the perioperative period is a frequent and clinically significant complication following major abdominal surgery and is associated with adverse outcomes, including increased postoperative complications, prolonged hospitalisation and worsened mortality.
A. Reynolds   +3 more
wiley   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng   +4 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Neuroprotective and antioxidant effects of ghrelin in an experimental glaucoma model

open access: yes, 2015
Nagehan Can,1 Onur Catak,2 Burak Turgut,2 Tamer Demir,2 Nevin Ilhan,3 Tuncay Kuloglu,4 Ibrahim Hanifi Ozercan5 1Department of Ophthalmology, Elaziğ Training and Research Hospital, 2Department of Ophthalmology, 3Department of Biochemistry, 4Department of
Turgut B   +6 more
core  

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma   +9 more
wiley   +1 more source

Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice

open access: yes, 2015
Yuqing Mao,1 Jianbo Wang,2 Fujun Yu,1 Jian Cheng,1 Huanqing Li,1 Chuanyong Guo,3 Xiaoming Fan11Department of Gastroenterology and Hepatology, Jinshan Hospital of Fudan University, Shanghai, 2Department of Gastroenterology and Hepatology, The Central ...
Mao YQ   +6 more
core  

How Shift Work Impacts on Eating Behaviours Among Nurses: A Cross‐Sectional Study

open access: yesNursing Open, Volume 13, Issue 10, October 2026.
ABSTRACT Aim To evaluate differences in eating behaviours between nurses working exclusively daytime shifts and those engaged in night shift work. Background A growing body of evidence suggests that night shift work exposed nurses to an increased risk of chronic conditions, including diabetes, metabolic syndrome, cardiovascular disease and cancer ...
Yun‐Chen Chang, Rocco Mea, Elsa Vitale
wiley   +1 more source

Energy homeostasis : crosstalk between adipose tissue and the human hypothalamus [PDF]

open access: yes
There is a worldwide epidemic of obesity. Weight rise is a consequence of continuous positive energy balance which leads to accumulation of body fat. Recent insights into adipose tissue (AT) biology have led to the conclusion that the adipocyte is not
Kos, Katarina
core  

Real‐World Outcomes of Telemedicine Shared Medical Appointments in Obesity Management

open access: yesObesity Science &Practice, Volume 12, Issue 5, October 2026.
ABSTRACT Introduction Shared Medical Appointments (SMAs) have recently emerged as a novel tool in weight management as they are efficient, bypass logistic barriers to physical attendance, decrease attrition, and are cost‐effective. This study aimed to observe outcomes among patients enrolled in an insurance‐based weight loss program, called Program for
Keerthana Haridas   +5 more
wiley   +1 more source

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