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Serum LEAP-2 as a Potential Biomarker for Hepatic Steatosis in Adolescents with Obesity and MASLD: A Cross-Sectional Study. [PDF]
Çakar S +7 more
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Comment on: "The role of EPAS-1 and ghrelin in right ventricular dysfunction in systemic lupus erythematosus". [PDF]
Hayıroğlu SC.
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Current Biology, 2023
López and Nogueiras introduce the peptide ghrelin and its physiological functions, including its roles in stimulating appetite and growth hormone release.
Miguel, López, Ruben, Nogueiras
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López and Nogueiras introduce the peptide ghrelin and its physiological functions, including its roles in stimulating appetite and growth hormone release.
Miguel, López, Ruben, Nogueiras
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The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism.In this review, we discuss the diverse biological functions of ghrelin ...
Ruben Nogueiras +2 more
exaly +9 more sources
From Ghrelin to Ghrelin's O-Acyl Transferase
2012The hormone ghrelin is a unique signaling peptide with powerful metabolic effects, mediated by its acylated forms. The acyl modification of ghrelin is unique in that it takes place via a susceptible ester linkage in the conserved serine-3 of ghrelin and is composed principally of octanoyl and, to lesser extent, decanoyl fatty acids.
Jesus A, Gutierrez +7 more
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Transgenic Mice Overexpressing Ghrelin or Ghrelin Analog
2012To understand the chronic effects of ghrelin, genetically engineered mouse models would be useful. Early studies, however, suggested that it was challenging to generate ghrelin gain-of-activity models by standard procedures. Although several groups have been trying to generate transgenic (Tg) mice overexpressing ghrelin, almost all these animals ...
Hiroyuki, Ariyasu +5 more
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