Results 131 to 140 of about 1,268,458 (245)

The Growth and Trends in Cancer‐Induced Cachexia Research: A Bibliometric and AI‐Guided Visualization Analysis

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Over the past several decades, advances in basic and clinical research have increasingly established cancer‐induced cachexia as a distinct pathophysiological syndrome that warrants targeted therapeutic approaches alongside conventional anticancer treatments. Despite its high prevalence and substantial impact on morbidity, mortality,
Thomas M. O'Connell, Radhika Gedela, Fabrizio Pin   +2 more
wiley   +1 more source

Ablation of Ghrelin Receptor Mitigates the Metabolic Decline of Aging Skeletal Muscle. [PDF]

Genes (Basel), 2022
O'Reilly C, Lin L, Wang H, Fluckey J, Sun Y.   +4 more
europepmc   +1 more source

Gastric Emptying in Obesity and Weight‐Loss Interventions: Physiology, Assessment, and Clinical Implications

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Obesity is associated with accelerated gastric emptying. Weight‐loss interventions each impose a distinct emptying signature: acceleration after sleeve gastrectomy and gastric bypass, delay after endoscopic sleeve gastroplasty, intragastric balloon, and GLP‐1 receptor agonists.
Maxime Amoyel, Rachida Lebtahi, Tigran Poghosyan, Maude Le Gall, Heithem Soliman   +4 more
wiley   +1 more source

Ghrelin Receptor Ligands: Design and Synthesis of Pseudopeptides and Peptidomimetics.

, 2013
International audienceMainly synthesized in the stomach, ghrelin is a peptide hormone which stimulates growth hormone secretion and appetite, thus promoting food intake and body-weight gain.
Gavara, Laurent, Moulin, Aline, Martinez, Jean, Brunel, Luc, Verdié, Pascal, Fehrentz, Jean-Alain   +5 more
core   +1 more source

Ghrelin Drives Food Intake by Attentional Bias Toward Food Cues

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Fasting and ghrelin enhanced engagement with food‐predictive cues in a home‐cage FED3 task, increasing correct and premature responses while reducing omissions. However, ghrelin preferentially increased food intake when food availability was signaled by a predictive cue, whereas fasting increased intake regardless of cue context.
Renée Poelman, Marie V. Le May, Iris Stoltenborg, Edoardo Vecchi, Erik Schéle, Roger A. H. Adan, Suzanne L. Dickson   +6 more
wiley   +1 more source

Ghrelin receptor (GHS-R1A) antagonism suppresses both operant alcohol self-administration and high alcohol consumption in rats

, 2011
The mechanisms involved in alcohol use disorders are complex. It has been shown that ghrelin is an important signal for the control of body weight homeostasis, preferably by interacting with hypothalamic circuits, as well as for drug reward by activating
Landgren, Sara, Sara Landgren, Engel, Jörgen A., Bartlett, Selena E., Jerlhag, Elisabet, Elisabet Jerlhag, Bartlett, SE, Hyytiä, Petri, Simms, Jeffrey A., Jeffrey A. Simms, Petri Hyytiä, Selena E. Bartlett, Engel, Jörgen,, Jörgen A. Engel, Simms, JA, Hyytiä, P, Landgren, Sara,, Jerlhag, Elisabeth,   +17 more
core   +1 more source

Modulating the Gut–Ovarian Axis: Mechanistic Rationale and the Limits of Current Evidence for Probiotics in Female Reproductive Aging

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Selected orally administered probiotics and functional‐food interventions may alter gut microbial ecology and intestinal barrier function. Microbiota‐derived metabolites, microbial components, and endocrine signals—including short‐chain fatty acids, bile acids, tryptophan metabolites, and lipopolysaccharide—may influence systemic immune, metabolic, and
Meiqi Chen, Qi Su, Mengshuang Sun, He Zhang, Jin Xu, Chenxi Zhang, Yanbo Wang   +6 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of Perioperative Muscle Wasting Following Major Abdominal Surgery

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Muscle wasting in the perioperative period is a frequent and clinically significant complication following major abdominal surgery and is associated with adverse outcomes, including increased postoperative complications, prolonged hospitalisation and worsened mortality.
A. Reynolds, N. M. George, A. Papadopoulou, B. Creagh‐Brown   +3 more
wiley   +1 more source

Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor. [PDF]

J Med Chem, 2022
Giorgioni G, Del Bello F, Quaglia W, Botticelli L, Cifani C, Micioni Di Bonaventura E, Micioni Di Bonaventura MV, Piergentili A.   +7 more
europepmc   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source