Results 161 to 170 of about 1,268,458 (245)
Discovery of a functionally selective ghrelin receptor (GHSR1a) ligand for modulating brain dopamine. [PDF]
Gross JD +17 more
europepmc +1 more source
Abstract Human binge eating disorder is characterized by recurrent episodes of excessive food consumption accompanied by loss of control and is strongly associated with alterations in reward processing and emotional regulation. Ayahuasca, a psychoactive botanical preparation traditionally used in Amazonian medicine, has been shown to modulate ...
Cristian Ferreira Corona +10 more
wiley +1 more source
Initial Pharmacological Characterization of a Major Hydroxy Metabolite of PF-5190457: Inverse Agonist Activity of PF-6870961 at the Ghrelin Receptor. [PDF]
Deschaine SL +14 more
europepmc +1 more source
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye +6 more
wiley +1 more source
Novel Role of Ghrelin Receptor in Gut Dysbiosis and Experimental Colitis in Aging. [PDF]
Noh JY +8 more
europepmc +1 more source
Abstract Nutrient sensing enables the body to detect and respond to nutrient availability through hormonal regulation. In this study, we examined nutrient‐stimulated hormonal responses in children with severe acute malnutrition (SAM) compared with hospitalized (HC) and community (CC) child comparators.
Ellen Besa +9 more
wiley +1 more source
Anorexia nervosa is associated with increased intestinal glucose uptake and altered ratio of glucose uptake into skeletal muscle versus subcutaneous adipose tissue during systemic hyperinsulinemia. Abstract Anorexia nervosa (AN) has been linked to both impaired and improved whole‐body insulin sensitivity, but tissue‐specific metabolic alterations ...
Aino Latva‐Rasku +16 more
wiley +1 more source
Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren. [PDF]
Liu H +6 more
europepmc +1 more source
This cross‐sectional study involving 937 adults at high cardiovascular risk found a positive association between short sleep duration (< 7 h/night) and traditional and non‐traditional markers of adiposity (abdominal obesity, overweight, and high visceral adiposity index [VAI]), a non‐traditional marker of glucose metabolism disruption (high ...
Nathallia Maria Cotta e Oliveira +5 more
wiley +1 more source

