Results 161 to 170 of about 20,015 (204)
Some of the next articles are maybe not open access.
Changes in ghrelin and ghrelin receptor expression according to feeding status
NeuroReport, 2003Ghrelin, a newly identified gut hormone, has been implicated in the regulation of food intake and energy homeostasis. This study was undertaken to investigate changes in expression levels of stomach ghrelin as well as of ghrelin receptor in the hypothalamus and pituitary glands according to feeding state.
Min-Seon, Kim +7 more
openaire +2 more sources
Diminished Endometrial Expression of Ghrelin and Ghrelin Receptor Contributes to Infertility
Reproductive Sciences, 2010The objectives were to investigate the presence, distribution and sex steroid hormone regulation of ghrelin and its receptor, growth hormone secretagogue receptor (GHSR), in human endometrium in relation to endometrial receptivity and fertility. Endometrial biopsies were obtained from women with unexplained infertility and healthy fertile volunteers ...
Lusine, Aghajanova +4 more
openaire +2 more sources
Cell Biology of the Ghrelin Receptor
Journal of Neuroendocrinology, 2005AbstractGhrelin, a gastric peptide involved in growth hormone release and energy homeostasis, is the endogenous ligand of the growth hormone secretagogue receptor type 1a (GHS‐R1a), a G‐protein coupled receptor mainly expressed in the pituitary and hypothalamus.
openaire +2 more sources
Recent Developments in Ghrelin Receptor Ligands
ChemInform, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Aline, Moulin +3 more
openaire +2 more sources
Cellular Signalling, 2007
The dimerization properties of the ghrelin receptor (GRLN-R) and its non-signalling, naturally occurring, truncated splice variant (GHS-R1b) have been investigated in human embryonic kidney 293 cells heterologously expressing these proteins. Using the techniques of bioluminescence resonance energy transfer and co-immunoprecipitation, we detected the ...
Chu, Kit Man +6 more
openaire +4 more sources
The dimerization properties of the ghrelin receptor (GRLN-R) and its non-signalling, naturally occurring, truncated splice variant (GHS-R1b) have been investigated in human embryonic kidney 293 cells heterologously expressing these proteins. Using the techniques of bioluminescence resonance energy transfer and co-immunoprecipitation, we detected the ...
Chu, Kit Man +6 more
openaire +4 more sources
Ala-scan of ghrelin (1–14): interaction with the recombinant human ghrelin receptor [PDF]
Peptides, 2004 Ghrelin, a 28 residues acylated peptide, is the natural ligand of the growth-hormone secretagogue receptor (GHS-R), which also interacts with small synthetic peptides. We investigated the importance of each of the first 14 N-terminal residues by Ala replacement (Ala-scan) and also of the N-terminal positive charge, on the recombinant GHS-R expressed in
Van Craenenbroeck, Mélanie +4 more
openaire +2 more sources
Ghrelin Receptor Mutations and Human Obesity
2016Growth hormone secretagogue receptor (GHSR) was originally identified as an orphan receptor in porcine and rat anterior pituitary membranes. In 1999, GHSR was deorphanized and shown to be a receptor for ghrelin, a peptide hormone secreted from the stomach. Therefore, GHSR is also called ghrelin receptor.
W, Wang, Y-X, Tao
openaire +2 more sources
Central functions of the ghrelin receptor
2014The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others.
Portelli, Jeanelle, Smolders, Ilse
openaire +3 more sources
General and Comparative Endocrinology, 2006
Ghrelin, a peptide hormone produced by the stomach in mammals, stimulates growth hormone release and food intake. Recently, ghrelin was identified and characterized in chicken proventriculus and shown to stimulate growth hormone release but inhibit feed intake.
Mark P, Richards +2 more
openaire +2 more sources
Ghrelin, a peptide hormone produced by the stomach in mammals, stimulates growth hormone release and food intake. Recently, ghrelin was identified and characterized in chicken proventriculus and shown to stimulate growth hormone release but inhibit feed intake.
Mark P, Richards +2 more
openaire +2 more sources
Neuropharmacology, 2010
Obesity has reached epidemic proportions not only in Western societies but also in the developing world. Current pharmacological treatments for obesity are either lacking in efficacy and/or are burdened with adverse side effects. Thus, novel strategies are required.
Harriët, Schellekens +2 more
openaire +2 more sources
Obesity has reached epidemic proportions not only in Western societies but also in the developing world. Current pharmacological treatments for obesity are either lacking in efficacy and/or are burdened with adverse side effects. Thus, novel strategies are required.
Harriët, Schellekens +2 more
openaire +2 more sources