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Constitutive Activity of the Ghrelin Receptor
2014Cloning and characterization of the ghrelin receptor as a 7-transmembrane (7TM), G-protein-coupled receptor (GPCR) was first reported by Howard and his co-workers (1996). The ghrelin receptor was initially described as a growth hormone secretagogue receptor since (GHSR) this was the most well-established physiological function at that time. The natural
Jacek Mokrosiński +2 more
openaire +1 more source
Homodimerization and Heterodimerization of the Ghrelin Receptor
2014Ghrelin triggers different metabolic and behavioral effects. This suggests that the GHSR may act synergistically with other families of receptors. Two isoforms of GHSR have been identified, i.e., GHSR-1a and GHSR-1b. Only GHSR-1a is the active form and transduces ghrelin signal.
Alessandro Laviano, Alessia Mari
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Targeting the Ghrelin Receptor as a Novel Therapeutic Option for Epilepsy
Biomedicines, 2022An Buckinx +2 more
exaly
Growth hormone-releasing hormone as an agonist of the ghrelin receptor GHS-R1a
Proceedings of the National Academy of Sciences of the United States of America, 2008Jesus Perez-Camiña, Felipe F Casanueva
exaly
The potential autocrine/paracrine roles of ghrelin and its receptor in hormone-dependent cancer
Cytokine and Growth Factor Reviews, 2003Adrian Herington, Penny Jeffery
exaly