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ChemMedChem, 2021
AbstractGhrelin is a pleiotropic feeding hormone which also has a pivotal role in the central nervous system. Upon the activation of its receptor, growth hormone secretagogue receptor (GHSR), the Gαq/11‐mediated and the β‐arrestin‐mediated signaling pathways are activated. As the β‐arrestin pathway is a potential drug target, there is a strong need for
Fumika Karaki +7 more
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AbstractGhrelin is a pleiotropic feeding hormone which also has a pivotal role in the central nervous system. Upon the activation of its receptor, growth hormone secretagogue receptor (GHSR), the Gαq/11‐mediated and the β‐arrestin‐mediated signaling pathways are activated. As the β‐arrestin pathway is a potential drug target, there is a strong need for
Fumika Karaki +7 more
openaire +2 more sources
Liraglutide Induces Enhanced Suppression of Food Intake in Ghsr-Deficient Mice
Mario Perello +9 more
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Associations of polymorphism within the GHSR gene with growth traits in Nanyang cattle
Molecular Biology Reports, 2009GH secretagogue receptor (ghrelin receptor, GHSR) is known to be involved in the control of GH release by mediating the strong stimulatory effect of the endogenous ligand, ghrelin, on GH secretion. Associations between the GHSR gene polymorphism and the growth traits were revealed in Nanyang cattle.
Bao, Zhang +10 more
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МЕТИЛЮВАННЯ ГЕНА GHSR ПРИ НЕОПЛАСТИЧНИХ ПРОЦЕСАХ ПОРОЖНИНИ РОТА
Scientific and practical journal "Stomatological Bulletin"Аберрантні патерни метилювання ДНК розглядають як чутливі та специфічні маркери раннього канцерогенезу, здатні вдосконалити діагностику злоякісних пухлин. Одним із перспективних епігенетичних показників є гіперметилювання гена рецептора стимулювального гормону росту (GHSR), яке корелює з інвазивністю та несприятливим прогнозом низки онкопроцесів.З ...
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GHSR signalling in perinatal phases is involved in liver metabolism at puberty
Journal of EndocrinologyGhrelin has effects that range from the maturation of the central nervous system to the regulation of energy balance. The production of ghrelin increases significantly during the first weeks of life. Studies have addressed the metabolic effects of liver-expressed antimicrobial peptide 2 (LEAP2) in inhibiting the effects evoked by ghrelin, mainly in ...
Marcos Divino Ferreira-Junior +6 more
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Progress in Neuro-Psychopharmacology and Biological Psychiatry
Ghrelin is a gastrointestinal hormone on feeding and metabolism regulation, and acts through its receptor-growth hormone secretagogue receptor (GHSR), which is widely distributed throughout the central nervous system. Recent studies have suggested that ghrelin plays an important role in the regulation of depression, but the underlying mechanisms remain
Leilei, Chang, Fengnan, Niu, Bin, Li
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Ghrelin is a gastrointestinal hormone on feeding and metabolism regulation, and acts through its receptor-growth hormone secretagogue receptor (GHSR), which is widely distributed throughout the central nervous system. Recent studies have suggested that ghrelin plays an important role in the regulation of depression, but the underlying mechanisms remain
Leilei, Chang, Fengnan, Niu, Bin, Li
openaire +2 more sources
GHSR: Growth Hormone Secretagogue Receptor
2016Yue Yin, Shiying Liu, Weizhen Zhang
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Mo1764 - Validation of GHSR Methylation as a Biomarker of Colorectal Cancer
Gastroenterology, 2018Fabio Coppedè +5 more
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