TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
A rare case of super giant basal cell carcinoma. [PDF]
Desmond B, Boudreaux L, Young J.
europepmc +3 more sources
Explainable human‐in‐the‐loop healthcare image information quality assessment and selection
Abstract Smart healthcare applications cannot be separated from healthcare data analysis and the interactive interpretability between data and model. A human‐in‐the‐loop active learning approach is introduced to reduce the cost of healthcare data labelling by evaluating the information quality of unlabelled medical data and then screening the high ...
Yang Li, Sezai Ercisli
wiley +1 more source
HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis [PDF]
Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous ...
A Ouban +58 more
core +1 more source
Cutis verticis gyrata in a patient with multiple basal cell carcinomas; case presentation and review of the literature [PDF]
Cutis verticis gyrata is a rare disease characterized by convoluted folds and deep furrows of the scalp, resembling the gyri and sulci of the cerebral cortex.
Benea, Vasile +6 more
core +4 more sources
Could the super-pulsed CO2 laser be used for oral excisional biopsies? [PDF]
Background. The main purpose of a biopsy is microscopic examination and diagnosis. Keeping the margins of specimens safe and readable is always fundamental to detecting marginal infiltrations or malignant transformation.
Ambrogiano, Simone +6 more
core +1 more source
Giant Basal Cell Carcinoma of the Lumbosacral Region: A Case Report and Literature Review [PDF]
Objective: Although frequently regarded as a low grade malignancy, basal cell carcinoma (BCC) sometimes shows aggressive behavior. Giant BCC is defined as a lesion greater then 5 centimeter.
Arzu Akçal +4 more
doaj +1 more source
Neglected Giant Scalp Basal Cell Carcinoma
Summary: Rarely, basal cell carcinoma grows to a giant size, invading the underlying deep tissue and complicating the treatment and reconstruction modalities.
Anne Kristine Larsen, MD +3 more
doaj +1 more source
Case report. A rare case of giant basal cell carcinoma and malignant melanoma [PDF]
The presence of two several skin lesions in the same patient is a rare occurrence in dermatological findings. The associations of malignant melanoma (MM) and giant basal cell carcinoma (BCC) within the same patient have only been described in few cases
Izzo, L. +3 more
core +1 more source
Giant basal cell carcinoma Carcinoma basocelular gigante
The basal cell carcinoma is the most common skin cancer but the giant vegetating basal cell carcinoma reaches less than 0.5 % of all basal cell carcinoma types.
Nilton Nasser +3 more
doaj +1 more source

