Results 101 to 110 of about 19,171 (192)

Production of Isolated Giant Unilamellar Vesicles under High Salt Concentrations

Frontiers in Physiology, 2017
The cell membrane forms a dynamic and complex barrier between the living cell and its environment. However, its in vivo studies are difficult because it consists of a high variety of lipids and proteins and is continuously reorganized by the cell ...
H. Stein, S. Spindler, Navid Bonakdar, Chun Wang, V. Sandoghdar   +4 more
semanticscholar   +1 more source

Janus Polymeric Nanorods Inhibit human Amylin Oligomerization and Fibrillation for Potential Type 2 Diabetes Treatment

Small Science, Volume 6, Issue 7, July 2026.
We demonstrate that polymeric Janus nanorods (JNRs) delay both oligomerization and fibrillation of human islet amyloid polypeptide (hIAPP) through high‐affinity and sequence‐specific interactions. JNRs display a β‐hairpin mimetic ligand (LP2) on one face, enabling multivalent binding.
Mathilde Jégo, Sandra Kalem, Irene Antignano, David Siefker, Mingsheng Ji, Julia Kaffy, Lynda Benrabah, Chloé Cayrou, Kawthar Bouchemal, Mélanie Hery, Erwan Nicol, Sandrine Pensec, Jutta Rieger, Claire Smadja, Sandrine Ongeri, Laurent Bouteiller, Olivier Colombani, Myriam Taverna   +17 more
wiley   +1 more source

Freeze‐thaw Fusion Enables Multi‐component Delivery and Protein Synthesis in POPG‐containing Lipid Vesicles

ChemSystemsChem, Volume 8, Issue 4, July 2026.
POPG‐containing membranes reduce leakage during freeze–thaw fusion, enabling efficient multi‐component delivery and protein synthesis inside GUVs. ABSTRACT Fusion between giant unilamellar vesicles (GUVs) provides a simple way to deliver and mix biochemical substrates within compartments surrounded by phospholipid membrane.
Tsubasa Yamashina, Masaya Oki, Gakushi Tsuji   +2 more
wiley   +1 more source

Induced phagocytic particle uptake into a giant unilamellar vesicle

Soft Matter, 2014
Phagocytosis, the uptake and ingestion of solid particles into living cells, is a central mechanism of our immune system. Due to the complexity of the uptake mechanism, the different forces involved in this process are only partly understood. Therefore the usage of a giant unilamellar vesicle (GUV) as the simplest biomimetic model for a cell allows one
Meinel, Andreas, Tränkle, Benjamin, Römer, Winfried, Rohrbach, Alexander   +3 more
openaire   +4 more sources

Charged giant unilamellar vesicles prepared by electroformation exhibit nanotubes and transbilayer lipid asymmetry

Scientific Reports, 2018
Giant unilamellar vesicles (GUVs) are increasingly used as a versatile research tool to investigate membrane structure, morphology and phase state. In these studies, GUV preparation is typically enhanced by an externally applied electric field, a process
Jan Steinkühler, Philippe De Tillieux, Roland L. Knorr, R. Lipowsky, R. Dimova   +4 more
semanticscholar   +1 more source

Dynamic and Sequential Protein Reconstitution on Negatively Curved Membranes by Giant Vesicles Fusion

Bio-Protocol, 2019
In vitro investigation of the interaction between proteins and positively curved membranes can be performed using a classic nanotube pulling method.
Nicola Franceschi, Maryam Alqabandi, Winfried Weissenhorn, Patricia Bassereau   +3 more
doaj   +1 more source

High-Efficiency Drug Loading in Lipid Vesicles by MEMS-Driven Gigahertz Acoustic Streaming

Micromachines
Drug carriers hold significant promise for precision medicine but face persistent challenges in balancing high encapsulation efficiency with structural preservation during active loading.
Bingxuan Li, Haopu Wang, Zhen Wang, Huikai Xie, Yao Lu   +4 more
doaj   +1 more source

Interaction of Giant Unilamellar Vesicles with the Surface Nanostructures on Dragonfly Wings.

Langmuir, 2019
The waxy epicuticle of dragonfly wings contains a unique nanostructured pattern that exhibits bactericidal properties. In light of emerging concerns of antibiotic resistance, these mechano-bactericidal surfaces represent a particularly novel solution by ...
S. Cheeseman, V. K. Truong, V. Walter, F. Thalmann, C. Marques, E. Hanssen, J. Vongsvivut, M. Tobin, V. Baulin, S. Juodkazis, S. Maclaughlin, G. Bryant, R. Crawford, E. Ivanova   +13 more
semanticscholar   +1 more source

DNA Origami Assembly Inside Liposomes via Nanopore‐Mediated DNA Transportation

Small Structures
Assembly of DNA origami nanostructures inside giant unilamellar vesicles (GUVs) is demonstrated by supplying approximately 200 unique staple strands from the external environment.
Shoji Iwabuchi, Kengo Kurematsu, Kazuya Yokoo, Yusuke Sakai, Yoshihiro Shimizu, Ryuji Kawano   +5 more
doaj   +1 more source

Benefits of Combined Fluorescence Lifetime Imaging Microscopy and Fluorescence Correlation Spectroscopy for Biomedical Studies Demonstrated by Using a Liposome Model System

Biophysica
Drug delivery systems play a pivotal role in targeted pharmaceutical transport and controlled release at specific sites. Liposomes, commonly used as drug carriers, constitute a fundamental part of these systems.
Kristina Bruun, Hans-Gerd Löhmannsröben, Carsten Hille   +2 more
doaj   +1 more source