Results 91 to 100 of about 340,809 (186)

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches [PDF]

Artículo escrito por más de setenta autores.Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells.
Welsh, Joshua A., Tosar Rovira, Juan Pablo, O’Driscoll, Lorraine, Goberdhan, Deborah C. I.   +3 more
core   +1 more source

Captivated by Kinesin

Cytoskeleton, EarlyView.
ABSTRACT Few proteins have inspired as much curiosity as kinesin. Since its discovery 40 years ago, kinesin has become one of the best understood molecular machines in biology, yet it continues to reveal new questions about how cells organize and move their contents.
Ronald D. Vale
wiley   +1 more source

The Kinesin Speed Paradox Revisited: How Can Cargoes Move Faster Than Their Motors?

Cytoskeleton, EarlyView.
ABSTRACT Intracellular transport is essential for cellular organization and function. Kinesin‐1, the founding member of the kinesin superfamily, delivers a wide range of cargoes along microtubules. Since its discovery, extensive work has identified cargo–kinesin interactions and regulatory mechanisms.
Kanako Iwasaki, Yasushi Okada
wiley   +1 more source

A giant complex pelvic cystic lesion misdiagnosed as a seminal vesicle tumor: A rare case report of prostatic cyst

Urology Case Reports
Giant prostatic cysts are a rare condition. This case report describes a 53-year-old male patient who presented with acute urinary retention. Imaging studies revealed a giant cystic mass in the pelvic cavity, with septa and nodules, adjacent to the ...
Jianbin Gu, Cong Liu
doaj   +1 more source

Microfluidic production of monodisperse food‐additive polymer capsules for biological applications

Droplet, EarlyView.
Monodisperse TGPR polymer capsules are generated via a robust microfluidic approach exploiting droplet interface transfer across the oil‒water interface. Unlike lipid vesicles, these capsules offer high thermal stability and biocompatibility. They successfully demonstrated utility as robust bioreactors for in‐capsule PCR and bacterial cultivation ...
Yuki Gondo, Daiki Miyashita, Kazu Toyota, Mamiko Tsugane, Taro Toyota, Hiroaki Suzuki   +5 more
wiley   +1 more source

A Novel System of Self-Reproducing Giant Vesicles

, 2016
Novel self-reproducing giant vesicles, consisting of a vesicular amphiphile with an imine group in its hydrophobic chain, were constructed. This vesicular amphiphile, the product of a dehydrocondensation reaction between amphiphilic aldehyde and a ...
Taro Toyota (718469), Tadashi Sugawara (2176468), Katsuto Takakura (2649535)   +2 more
core   +1 more source

Pediatric new‐onset seizure‐like events: Yield of diagnostic work‐up

Epileptic Disorders, EarlyView.
Abstract Objective To assess the diagnostic yield of ancillary investigations in children presenting with new‐onset seizure‐like events (SLEs) at a tertiary first seizure clinic (FSC). Methods We conducted a retrospective cohort study including 1213 children evaluated for new‐onset SLEs at a tertiary FSC.
Geertruida Slinger, Lotte Noorlag, Willem M. Otte, Maeike Zijlmans, Rosalie L. Neijzen, Sandra M. A. van der Salm, Floor E. Jansen, Kees P. J. Braun, Eric van Diessen   +8 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Reconstitution of Active Plant H+-ATPase AHA2 in Giant Unilamellar Vesicles

Bio-Protocol
Membrane transporters mediate the selective movement of ions and molecules across biological membranes and are essential for cellular homeostasis. However, their functional characterization in living cells is often complicated by the complexity of the ...
Huriye Uzun, Thomas Pomorski
doaj   +1 more source